1 Hospital Universitari Vall d'Hebron, Barcelona, Spain.
2 Biomedical Network Research Center on Mental Health, Barcelona, Spain.
J Atten Disord. 2019 Oct;23(12):1514-1525. doi: 10.1177/1087054718780323. Epub 2018 Jun 12.
The objective of this study was to investigate the extent to which neuropsychological performance parameters implicated in ADHD might mediate the relationship between emotional lability (EL) and this disorder. Eight hundred twelve adult patients with ADHD were examined. EL was assessed using the EL subscale of Conners' Adult ADHD Rating Scales (CAARS). To assess cognitive and executive functions, a battery of neuropsychological tests was performed in 262 patients with ADHD and high EL symptomatology and 550 patients with ADHD and low EL symptomatology. Several differences between groups were found regarding neuropsychological performance; however, nearly all significant differences disappeared when the effect of gender, inattention, and hyperactive symptoms and psychiatric comorbidities were taken into account. Our results do not support the hypothesis that neuropsychological deficits are associated with EL in adults with ADHD.
这项研究的目的是调查神经心理学表现参数在多大程度上可能在情绪不稳定（EL）与 ADHD 之间的关系中起中介作用。 研究共检查了 812 名成年 ADHD 患者。 使用康纳斯成人 ADHD 评定量表（CAARS）的 EL 分量表评估 EL。为了评估认知和执行功能，对 262 名 ADHD 且 EL 症状严重和 550 名 ADHD 且 EL 症状较轻的患者进行了一系列神经心理学测试。 发现各组之间在神经心理学表现方面存在一些差异；但是，当考虑到性别、注意力不集中和多动症状以及精神共病的影响时，几乎所有的显著差异都消失了。 我们的结果不支持神经心理学缺陷与成人 ADHD 中 EL 相关的假设。
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