Suppr超能文献

胎儿小脑疾病。

Fetal cerebellar disorders.

作者信息

Lerman-Sagie Tally, Prayer Daniella, Stöcklein Sophia, Malinger Gustavo

机构信息

Fetal Neurology Clinic, Prenatal Ultrasound Unit, Department of Obstetrics and Gynecology, and Pediatric Neurology Unit, Wolfson Medical Center, Holon, Israel.

Division of Neuro- and Musculoskeletal Radiology, Department of Radiology, Medical University of Vienna, Vienna, Austria.

出版信息

Handb Clin Neurol. 2018;155:3-23. doi: 10.1016/B978-0-444-64189-2.00001-9.

Abstract

The embryologic development of the cerebellum extends over a long time period, thus making it vulnerable to a broad spectrum of malformations and disruptions. Knowledge of the main steps of fetal posterior fossa development; the normal imaging patterns at different stages of embryogenesis; the large spectrum of cerebellar malformations; and their clinical presentations enables diagnosis and precise counseling of parents. Sonography is the most important imaging method for the screening of cerebellar malformations since it is noninvasive, widely available, and safe for both mother and child. The ultrasonographic approach for the evaluation of the fetal posterior fossa is based on the classic transabdominal visualization of axial planes with addition when indicated of a more comprehensive, multiplanar transvaginal or transfundal approach, including coronal and sagittal imaging planes. Fetal magnetic resonance imaging (MRI) has become an adjunct to prenatal ultrasound since the 1980s. Good-quality images have been obtained thanks to the implementation of fast and ultrafast MRI sequences. Fetal MRI has higher-contrast resolution than prenatal sonography and may contribute to the differentiation of normal from abnormal tissue. Both prenatal neurosonography and fetal MRI enable accurate prenatal diagnosis of most posterior fossa anomalies.

摘要

小脑的胚胎发育持续很长一段时间,因此使其易受多种畸形和发育障碍的影响。了解胎儿后颅窝发育的主要步骤、胚胎发生不同阶段的正常影像学表现、小脑畸形的广泛类型及其临床表现,有助于进行诊断并为家长提供准确的咨询。超声检查是筛查小脑畸形最重要的影像学方法,因为它无创、广泛可用且对母婴均安全。评估胎儿后颅窝的超声检查方法基于经典的经腹轴向平面可视化,必要时可增加更全面的多平面经阴道或经腹途径,包括冠状面和矢状面成像平面。自20世纪80年代以来,胎儿磁共振成像(MRI)已成为产前超声的辅助手段。由于快速和超快MRI序列的应用,已获得高质量图像。胎儿MRI比产前超声具有更高的对比度分辨率,可能有助于区分正常组织和异常组织。产前神经超声检查和胎儿MRI都能对大多数后颅窝异常进行准确的产前诊断。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验