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糖尿病患者的门诊药物调整与住院和急诊就诊频率。

Ambulatory Medication Reconciliation and Frequency of Hospitalizations and Emergency Department Visits in Patients With Diabetes.

机构信息

Brigham and Women's Hospital, Boston, MA

Baim Institute for Clinical Research, Boston, MA.

出版信息

Diabetes Care. 2018 Aug;41(8):1639-1645. doi: 10.2337/dc17-1260. Epub 2018 Jun 11.

DOI:10.2337/dc17-1260
PMID:29891639
Abstract

OBJECTIVE

To investigate the association between ambulatory medication reconciliation and health care utilization in patients with diabetes.

RESEARCH DESIGN AND METHODS

In this retrospective cohort analysis, we studied adults taking at least one diabetes medication treated in primary care practices affiliated with two academic medical centers between 2000 and 2014. We assessed the relationship between the fraction of outpatient diabetes medications reconciled over a 6-month period and the composite primary outcome of combined frequency of emergency department (ED) visits and hospitalizations over the subsequent 6 months.

RESULTS

Among 261,765 reconciliation assessment periods contributed by 31,689 patients, 176,274 (67.3%), 27,775 (10.6%), and 57,716 (22.1%) had all, some, or none of the diabetes medications reconciled, respectively. Patients with all, some, or no diabetes medications reconciled had 0.354, 0.377, and 0.384 primary outcome events per 6 months, respectively ( < 0.0001). In a multivariable analysis adjusted for demographics and comorbidities, having some or all versus no diabetes medications reconciled was associated with a lower risk of the primary outcome (rate ratio 0.94 [95% CI 0.90-0.98; = 0.0046] vs. 0.92 [0.89-0.95; < 0.0001], respectively). Introduction of feedback to individual providers was associated with a significant increase in the odds of all diabetes medications being reconciled (2.634 [2.524-2.749]; < 0.0001).

CONCLUSIONS

A higher fraction of reconciled outpatient diabetes medications was associated with a lower frequency of ED visits and hospitalizations. Individual performance feedback could help to achieve more comprehensive medication reconciliation.

摘要

目的

研究门诊药物重整与糖尿病患者医疗保健利用之间的关联。

研究设计和方法

在这项回顾性队列分析中,我们研究了 2000 年至 2014 年间在两家学术医疗中心附属的基层医疗机构接受至少一种糖尿病药物治疗的成年人。我们评估了在 6 个月期间外配糖尿病药物重整比例与随后 6 个月内急诊就诊(ED)和住院的复合主要结局之间的关系。

结果

在 31689 名患者贡献的 261765 个重整评估期内,分别有 176274(67.3%)、27775(10.6%)和 57716(22.1%)患者的所有、部分或无糖尿病药物被重整。所有、部分或无糖尿病药物被重整的患者,其主要结局事件的发生率分别为每 6 个月 0.354、0.377 和 0.384 次(<0.0001)。在调整了人口统计学和合并症的多变量分析中,与无糖尿病药物重整相比,部分或全部糖尿病药物重整与较低的主要结局风险相关(发生率比 0.94[95%CI 0.90-0.98;=0.0046],0.92[0.89-0.95;<0.0001])。向个体提供者提供反馈与所有糖尿病药物被重整的可能性显著增加相关(比值比 2.634[2.524-2.749];<0.0001)。

结论

更多的外配糖尿病药物被重整与较低的 ED 就诊和住院频率相关。个体绩效反馈可能有助于实现更全面的药物重整。

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