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以胆囊炎和多发性单神经炎为表现的嗜酸性肉芽肿性多血管炎:一例报告

Eosinophilic Granulomatosis with Polyangiitis Manifested by Cholecystitis and Mononeuritis Multiplex: A Case Report.

作者信息

Mobini Maryam, Cheraghmakani Hamed, Torabizadeh Zhila, Emadian Omid, Nezhadi Kelarijani Fatemeh

机构信息

Diabetes Research Center, Department of Internal Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Department of Neurology, Bu Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran.

出版信息

Iran J Med Sci. 2018 May;43(3):332-335.

Abstract

Eosinophilic granulomatosis with polyangiitis formerly named "Churg-Strauss syndrome (CSS)" is a systemic disease with bronchial asthma, hypereosinophilia, and systemic vasculitis. We report a case of CSS with cholecystitis and mononeuritis multiplex. A 50-year-old woman with a history of sinusitis and bronchial asthma of 8 years' duration was referred with a complaint of left-hand deformity and difficulty in walking. The laboratory findings included remarkable eosinophilia, an elevated erythrocyte sedimentation rate, and a marked eosinophilic infiltration in the gallbladder biopsy. Based on the clinical features and histopathological findings, she was diagnosed with CSS and subsequently treated with prednisolone and cyclophosphamide.

摘要

嗜酸性肉芽肿性多血管炎,以前称为“变应性肉芽肿性血管炎(CSS)”,是一种伴有支气管哮喘、嗜酸性粒细胞增多和系统性血管炎的全身性疾病。我们报告一例伴有胆囊炎和多发性单神经炎的CSS病例。一名50岁女性,有8年鼻窦炎和支气管哮喘病史,因左手畸形和行走困难前来就诊。实验室检查结果包括显著的嗜酸性粒细胞增多、红细胞沉降率升高以及胆囊活检中有明显的嗜酸性粒细胞浸润。根据临床特征和组织病理学检查结果,她被诊断为CSS,随后接受泼尼松龙和环磷酰胺治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/387f/5993901/b795f903027c/IJMS-43-332-g001.jpg

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