Taha Diaa-Eldin, Shokeir Ahmed A, Aboumarzouk Omar A
Department of Urology, Faculty of Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Department of Urology, Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
Arab J Urol. 2018 Mar 2;16(2):197-205. doi: 10.1016/j.aju.2018.01.004. eCollection 2018 Jun.
To establish the current evidence and assess the effectiveness and safety of selective transarterial embolisation (STE) to control intractable bladder haemorrhage (IBH).
With a rise in the use of STE for the treatment of IBH, a systematic review was performed according to the Cochrane reviews guidelines and in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist.
The literature search yielded 38 studies, of which 11 were excluded because of irrelevance of data. All included studies were observational cohort studies, with no randomisation or control groups apart from in relation to the materials used for embolisation. The studies were published between 1978 and 2016. There were 295 patients with an age range between 51 and 95 years. The success rate ranged from 43% up to 100%. The most reported complication was post-embolisation syndrome, although other complications were described such as mild transient gluteal claudication, nausea, and vomiting.
STE of the internal iliac artery is a safe and effective alternative technique to control severe IBH, and has been successfully applied over many years to treat bladder haemorrhage associated with terminal pelvic malignancy.
确立当前证据,并评估选择性经动脉栓塞术(STE)控制难治性膀胱出血(IBH)的有效性和安全性。
随着STE用于治疗IBH的应用增加,根据Cochrane综述指南并按照系统评价与Meta分析的首选报告项目(PRISMA)清单进行了一项系统评价。
文献检索得到38项研究,其中11项因数据不相关而被排除。所有纳入研究均为观察性队列研究,除了用于栓塞的材料外,没有随机分组或对照组。这些研究发表于1978年至2016年之间。有295例患者,年龄范围在51至95岁之间。成功率在43%至100%之间。最常报告的并发症是栓塞后综合征,不过也描述了其他并发症,如轻度短暂性臀肌跛行、恶心和呕吐。
髂内动脉STE是控制严重IBH的一种安全有效的替代技术,多年来已成功应用于治疗与晚期盆腔恶性肿瘤相关的膀胱出血。