Carlson H E, Brickman A S, Burns T W, Langley P E
J Clin Endocrinol Metab. 1985 Aug;61(2):382-4. doi: 10.1210/jcem-61-2-382.
The lipolytic response to isoproterenol infusion was examined in seven normal subjects and six patients with pseudohypoparathyroidism type I [two had deficiency of the hormone receptor-cyclase coupling protein (N-protein) and four did not]. Despite blunted plasma cAMP responses to isoproterenol in both subgroups of pseudohypoparathyroidism patients, the serum FFA responses were normal. We conclude that changes in plasma cAMP do not reflect the adequacy of the lipolytic response to isoproterenol.
在7名正常受试者和6名I型假性甲状旁腺功能减退患者[其中2名缺乏激素受体-环化酶偶联蛋白（N蛋白），4名不缺乏]中检测了对异丙肾上腺素输注的脂解反应。尽管假性甲状旁腺功能减退患者的两个亚组对异丙肾上腺素的血浆cAMP反应均减弱，但血清游离脂肪酸反应正常。我们得出结论，血浆cAMP的变化并不反映对异丙肾上腺素脂解反应的充分性。
