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异基因干细胞移植后中剂量阿糖胞苷治疗双侧乳腺髓系肉瘤:1例报告及文献复习

Intermediate dose cytarabine in treatment myeloid sarcoma of the bilateral breast after allogeneic stem cell transplantation: A case report and literature review.

作者信息

Aznab Mozaffar, Khazaie Mansour

机构信息

Department of Internal Medicine, Taleghani Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Department of Pathology, Taleghani Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

J Cancer Res Ther. 2018 Apr-Jun;14(3):703-705. doi: 10.4103/0973-1482.174174.

Abstract

Myeloid sarcoma can be occurred bofore acute myeloid leukemia, concomitantly, at relapse or after allogenic stem cell transplantation, rarely. In this investigation, we reported a 38-year-old woman with a history of AML relapsed 9 months after allo-SCT as an MS in the bilateral breast. She underwent bilateral mastectomy. The patient was a candidate for systemic chemotherapy. An intermediate dose of cytarabine with mitoxantrone was considered for the patient, and it was repeated at the specified intervals. Currently, the patient is still being followed up, and there is no sign of local or systemic recurrence.

摘要

髓系肉瘤很少在急性髓系白血病之前、同时、复发时或异基因干细胞移植后发生。在本研究中,我们报告了一名38岁女性,她在异基因造血干细胞移植后9个月复发急性髓系白血病,表现为双侧乳腺髓系肉瘤。她接受了双侧乳房切除术。该患者适合进行全身化疗。考虑为患者使用中等剂量阿糖胞苷联合米托蒽醌,并按规定间隔重复使用。目前,该患者仍在随访中,无局部或全身复发迹象。

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