Peddareddy Lakshmi, Merchant Faisal M, Leon Angel R, Smith Paige, Patel Akshar, El-Chami Mikhael F
Emory University School of Medicine, Atlanta, GA, USA.
Emory University School of Medicine, Department of Medicine, Division of Cardiology, Section of Electrophysiology, Emory University School of Medicine, Atlanta, GA, USA.
Pacing Clin Electrophysiol. 2018 Jun 12. doi: 10.1111/pace.13416.
Defibrillation threshold (DFT) testing is recommended with the subcutaneous implantable cardioverter defibrillator (SICD).
To describe first shock efficacy for appropriate SICD therapies stratified by the presence of implant DFT testing.
We reviewed all patients receiving SICDs at our institution and stratified them based on whether implant DFT testing was performed. Appropriate shocks were reviewed to see if ventricular tachycardia/ventricular fibrillation (VT/VF) terminated with a single shock. First shock efficacy was stratified by implant DFT status.
178 patients implanted with SICDs and followed in our center were included in this study. Of these, 135 (76%) underwent DFT testing (DFT (+) group). In the DFT (+), 80 appropriate shocks were needed to treat 69 episodes of VT/VF. The first shock was effective in 61 out of 69 episodes (88.4%), whereas multiple shocks were required to terminate VT/VF in the remaining eight episodes. Among 43 patients without implant DFT testing (DFT (-) group), 20 appropriate shocks to treat 17 episodes of VT/VF occurred in seven patients. VT/VF was successfully terminated with the first shock in 16 out of 17 episodes (first shock efficacy 94.1 %). There was no significant difference in first shock effectiveness between those with and without implant DFT testing (P = 0.97).
A strategy that omits DFT testing at implant did not appear to compromise the effectiveness of the SICD. These data suggest that routine DFT testing at SICD implant might not be necessary. Randomized trials are needed to confirm this finding.
皮下植入式心律转复除颤器(SICD)建议进行除颤阈值(DFT)测试。
描述根据植入时DFT测试情况分层的适当SICD治疗的首次电击疗效。
我们回顾了在本机构接受SICD治疗的所有患者,并根据是否进行植入时DFT测试对他们进行分层。对适当的电击进行评估,以确定室性心动过速/心室颤动(VT/VF)是否通过单次电击终止。首次电击疗效根据植入时DFT状态进行分层。
本研究纳入了178例在我们中心植入SICD并接受随访的患者。其中,135例(76%)进行了DFT测试(DFT(+)组)。在DFT(+)组中,治疗69次VT/VF发作需要80次适当的电击。69次发作中有61次(88.4%)首次电击有效,其余8次发作需要多次电击才能终止VT/VF。在43例未进行植入时DFT测试的患者(DFT(-)组)中,7例患者发生了20次适当的电击以治疗17次VT/VF发作。17次发作中有16次(首次电击疗效94.1%)首次电击成功终止了VT/VF。进行和未进行植入时DFT测试的患者之间首次电击有效性无显著差异(P = 0.97)。
植入时省略DFT测试的策略似乎并未损害SICD的有效性。这些数据表明,SICD植入时常规进行DFT测试可能没有必要。需要进行随机试验来证实这一发现。