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皮下植入式心脏复律除颤器植入过程中的除颤测试:一项必要标准还是变得多余?

Defibrillation testing during implantation of the subcutaneous implantable cardioverter-defibrillator: a necessary standard or becoming redundant?

作者信息

van der Stuijt W, Quast A B E, Knops R E

机构信息

Department of Cardiology, Heart Center, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

出版信息

Neth Heart J. 2020 Aug;28(Suppl 1):122-127. doi: 10.1007/s12471-020-01448-4.

Abstract

Since the publication of the SIMPLE and NORDIC trials, defibrillation testing (DFT) is rarely performed during routine implantation of transvenous implantable cardioverter-defibrillators (ICD). However, the results of these trials cannot be extrapolated to the later introduced subcutaneous ICD (S-ICD) and a class I recommendation to perform DFT during the implantation of these devices remains in the current guidelines. Due to the high conversion success rate of DFT on one hand, and the risk of complications on the other, a significant number of physicians omit DFT in S‑ICD recipients. Several retrospective analyses have assessed the safety of the omission of DFT and report contradicting results and recommendations. It is known that implant position, as well as device factors and patient characteristics, influence defibrillation success. A better comprehension of these factors and their relationship could lead to more reliable and safer alternatives to DFT. An ongoing randomised clinical trial, which is expected to end in 2023, is the first study to implement a method that assesses implant position to identify patients who are likely to fail their DFT.

摘要

自SIMPLE试验和北欧试验发表以来,经静脉植入式心律转复除颤器(ICD)常规植入过程中很少进行除颤阈值测试(DFT)。然而,这些试验的结果不能外推至后来推出的皮下ICD(S-ICD),并且在这些设备植入期间进行DFT的I类推荐仍保留在当前指南中。一方面由于DFT的高转换成功率,另一方面由于并发症风险,相当数量的医生在S-ICD接受者中省略了DFT。多项回顾性分析评估了省略DFT的安全性,并报告了相互矛盾的结果和建议。已知植入位置以及设备因素和患者特征会影响除颤成功率。更好地理解这些因素及其关系可能会带来比DFT更可靠、更安全的替代方法。一项预计于2023年结束的正在进行的随机临床试验,是第一项采用评估植入位置以识别可能DFT失败患者的方法的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/864b/7419406/50b400151c26/12471_2020_1448_Fig1_HTML.jpg

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