慢性髓性白血病儿童和青年中ASXL1突变频繁。 - Suppr

Frequent ASXL1 mutations in children and young adults with chronic myeloid leukemia.

作者信息

Ernst Thomas, Busch Melinda, Rinke Jenny, Ernst Jana, Haferlach Claudia, Beck James F, Hochhaus Andreas, Gruhn Bernd

机构信息

Abteilung Hämatologie und Internistische Onkologie, Klinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Germany.

Sektion für Hämatologie, Onkologie und Stammzelltransplantation, Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Jena, Jena, Germany.

出版信息

Leukemia. 2018 Sep;32(9):2046-2049. doi: 10.1038/s41375-018-0157-2. Epub 2018 Jun 13.

DOI:10.1038/s41375-018-0157-2

PMID:29899367

Abstract

摘要

相似文献

Frequent ASXL1 mutations in children and young adults with chronic myeloid leukemia.慢性髓性白血病儿童和青年中ASXL1突变频繁。

Leukemia. 2018 Sep;32(9):2046-2049. doi: 10.1038/s41375-018-0157-2. Epub 2018 Jun 13.

ASXL1 and JAK2V617F gene mutation screening in Iranian patients with chronic myeloid leukemia.伊朗慢性髓性白血病患者中ASXL1和JAK2V617F基因突变筛查

Asia Pac J Clin Oncol. 2017 Apr;13(2):e41-e47. doi: 10.1111/ajco.12588. Epub 2016 Sep 19.

Mutational analysis in BCR-ABL1 positive leukemia by deep sequencing based on nanopore MinION technology.基于纳米孔MinION技术的深度测序对BCR-ABL1阳性白血病进行突变分析。

Exp Mol Pathol. 2017 Aug;103(1):33-37. doi: 10.1016/j.yexmp.2017.06.007. Epub 2017 Jun 27.

Clinical significance of dual color-dual fusion translocation fluorescence in situ hybridization in the detection of bcr/abl fusion gene.双色-双融合易位荧光原位杂交技术检测bcr/abl融合基因的临床意义

Zhonghua Zhong Liu Za Zhi. 2002 Jul;24(4):364-6.

New mutations detected by denaturing high performance liquid chromatography during screening of exon 6 bcr-abl mutations in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors.在接受酪氨酸激酶抑制剂治疗的慢性髓性白血病患者中，通过变性高效液相色谱法筛选6号外显子bcr-abl突变时检测到的新突变。

Leuk Lymphoma. 2009 Jul;50(7):1148-54. doi: 10.1080/10428190902930496.

Mutations in ABL kinase domain are associated with inferior progression-free survival.ABL 激酶结构域的突变与较差的无进展生存期相关。

Leuk Lymphoma. 2010 Jun;51(6):1072-8. doi: 10.3109/10428191003729741.

Molecular monitoring of response to imatinib (Glivec) in chronic myeloid leukemia patients: experience at a tertiary care hospital in Saudi Arabia.慢性髓性白血病患者对伊马替尼（格列卫）反应的分子监测：沙特阿拉伯一家三级医疗医院的经验。

Genet Test Mol Biomarkers. 2010 Feb;14(1):67-74. doi: 10.1089/gtmb.2009.0126.

ETV6/ABL fusion is rare in Ph-negative chronic myeloid disorders.ETV6/ABL融合在Ph阴性慢性髓系疾病中罕见。

Leukemia. 1998 Jul;12(7):1167-8. doi: 10.1038/sj.leu.2401091.

[Dual-color/dual-fusion interphase fluorescence in situ hybridization probe for monitoring tumor load during imatinib therapy for chronic myeloid leukemia].[用于监测慢性髓性白血病伊马替尼治疗期间肿瘤负荷的双色/双融合间期荧光原位杂交探针]

Nan Fang Yi Ke Da Xue Xue Bao. 2010 Jan;30(1):123-5.

Prevalence of BCR-ABL T315I Mutation in Malaysian Patients with Imatinib-Resistant Chronic Myeloid Leukemia.马来西亚伊马替尼耐药慢性髓性白血病患者中BCR-ABL T315I突变的患病率

Asian Pac J Cancer Prev. 2018 Dec 25;19(12):3317-3320. doi: 10.31557/APJCP.2018.19.12.3317.

引用本文的文献

The biology of chronic myeloid leukemia: an overview of the new insights and biomarkers.慢性髓系白血病的生物学：新见解与生物标志物概述

Front Oncol. 2025 May 8;15:1546813. doi: 10.3389/fonc.2025.1546813. eCollection 2025.

Somatic mutations and outcomes in chronic myeloid leukemia adolescent and young adults compared to children, adults, and BCR::ABL1-positive acute lymphoblastic leukemia.与儿童、成人以及BCR::ABL1阳性急性淋巴细胞白血病相比，慢性髓性白血病青少年和年轻成人的体细胞突变与预后

Leukemia. 2025 Apr 28. doi: 10.1038/s41375-025-02609-3.

Molecular predictors of venous and arterial thrombotic events in patients with myelofibrosis.骨髓纤维化患者静脉和动脉血栓形成事件的分子预测指标

Ann Hematol. 2025 Apr 27. doi: 10.1007/s00277-025-06361-7.

Favorable outcomes of de novo advanced phases of pediatric chronic myeloid leukemia in the tyrosine kinase inhibitor era.酪氨酸激酶抑制剂时代儿童慢性髓性白血病初发晚期阶段的良好预后。

Int J Hematol. 2025 Mar 15. doi: 10.1007/s12185-025-03953-x.

A high proportion of germline variants in pediatric chronic myeloid leukemia.儿童慢性髓性白血病中存在大量种系变异。

Mol Cancer. 2024 Sep 26;23(1):206. doi: 10.1186/s12943-024-02109-5.

European LeukemiaNet laboratory recommendations for the diagnosis and management of chronic myeloid leukemia.欧洲白血病网络实验室关于慢性髓性白血病诊断和管理的建议。

Leukemia. 2023 Nov;37(11):2150-2167. doi: 10.1038/s41375-023-02048-y. Epub 2023 Oct 4.

Somatic variant profiling in chronic phase pediatric chronic myeloid leukemia.儿童慢性期慢性髓性白血病的体细胞变异分析

Haematologica. 2024 Mar 1;109(3):942-947. doi: 10.3324/haematol.2023.283800.

Prognosis in Chronic Myeloid Leukemia: Baseline Factors, Dynamic Risk Assessment and Novel Insights.慢性髓性白血病的预后：基线因素、动态风险评估和新的见解。

Cells. 2023 Jun 23;12(13):1703. doi: 10.3390/cells12131703.

A customized mass array panel for :: tyrosine kinase domain mutation screening in chronic myeloid leukemia.一种用于慢性髓性白血病酪氨酸激酶结构域突变筛查的定制化质谱分析芯片。

J Mass Spectrom Adv Clin Lab. 2023 Apr 13;28:122-132. doi: 10.1016/j.jmsacl.2023.04.002. eCollection 2023 Apr.

Children with chronic myeloid leukaemia treated with front-line imatinib have a slower molecular response and comparable survival compared with adults: a multicenter experience in Taiwan.台湾多中心经验：一线伊马替尼治疗的慢性髓性白血病儿童的分子反应较慢，但与成人相比生存相当。

Br J Cancer. 2023 Mar;128(7):1294-1300. doi: 10.1038/s41416-023-02162-9. Epub 2023 Jan 30.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Frequent ASXL1 mutations in children and young adults with chronic myeloid leukemia.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献