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妓女中乙型肝炎、单纯疱疹和巨细胞病毒抗体的发生率。

Incidences of antibodies to hepatitis B, herpes simplex and cytomegalovirus in prostitutes.

作者信息

Dannenmaier B, Alle W, Hoferer E W, Lorenz D, Oertel P J, Doerr H W

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A. 1985 Apr;259(2):275-83. doi: 10.1016/s0176-6724(85)80058-4.

DOI:10.1016/s0176-6724(85)80058-4
PMID:2990124
Abstract

The 170 prostitutes registered by the local public health authority (165 female, 5 male; ages 17-61) were serologically investigated by ELISA and CFT for the presence of hepatitis B virus (HBV) markers (n = 170), anti-CMV (n = 118) and anti-HSV 2 antibodies (n = 117). 4.7% (1.2%) were found to be HBs- (HBe-)antigen carriers; 1.2% revealed an acute hepatitis B (seroconversion of anti-HBc or IgM-anti-HBc highly positive); 17.1% presented a past and resolved hepatitis B (anti-HBs positive). These rates exceeded those of 125 female age-matched control persons considerably, out of whom only 2.4% (0.8%) presented HBs-(HBe-) antigen and 3.2% anti-HBs antibodies. 90% of the prostitutes investigated proved to be anti-CMV IgG (1.7% IgM) antibody positive and were compared to healthy blood donors (47% IgG, 0% IgM-anti-CMV antibody carriers) and other CMV risk groups: pregnant women 56 (13), patients in hemodialysis 61 (0), hemophiliac patients 69 (0), patients after kidney transplantation 90 (16) and after open-heart surgery 87 (4) % anti-CMV IgG (IgM) antibody carriers. An AIDS patient suffered from simultaneous HBV and CMV infections. The risk of HSV 2 infection is among prostitutes (38.5% seropositives) five times as high as among female age-matched control persons (7.2% seropositives, n = 125). These results confirm that prostitutes must be regarded as a risk for the spread of hepatitis BV and CMV- and HSV 2-caused diseases in the population.

摘要

当地公共卫生部门登记的170名妓女(165名女性,5名男性;年龄17 - 61岁)接受了酶联免疫吸附测定(ELISA)和补体结合试验(CFT)的血清学调查,以检测乙肝病毒(HBV)标志物(n = 170)、抗巨细胞病毒(CMV)抗体(n = 118)和抗单纯疱疹病毒2型(HSV 2)抗体(n = 117)。发现4.7%(1.2%)为乙肝表面抗原(HBe抗原)携带者;1.2%表现为急性乙型肝炎(抗HBc或IgM - 抗HBc血清学转换高度阳性);17.1%呈现既往感染且已痊愈的乙型肝炎(抗HBs阳性)。这些比率大大超过了125名年龄匹配的女性对照者,在这些对照者中,只有2.4%(0.8%)呈现乙肝表面抗原(HBe抗原),3.2%呈现抗HBs抗体。90%接受调查的妓女抗CMV IgG(1.7% IgM)抗体呈阳性,并与健康献血者(47% IgG,0% IgM - 抗CMV抗体携带者)及其他CMV风险组进行了比较:孕妇56(13)%、血液透析患者61(0)%、血友病患者69(0)%、肾移植术后患者90(16)%和心脏直视手术后患者87(4)%抗CMV IgG(IgM)抗体携带者。一名艾滋病患者同时感染了HBV和CMV。HSV 2感染风险在妓女中(38.5%血清阳性)是年龄匹配的女性对照者(7.2%血清阳性,n = 125)的五倍。这些结果证实,妓女必须被视为人群中乙肝病毒、CMV和HSV 2所致疾病传播的风险因素。

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