Prieto Bohórquez Signed Esperanza, Rodríguez Velásquez Javier Oswaldo, Correa Herrera Catalina, Pardo Oviedo Juan Mauricio, Ardila Javier
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Rev Fac Cien Med Univ Nac Cordoba. 2017 Dec 21;74(4):313-319. doi: 10.31053/1853.0605.v74.n4.16308.
an exponential law has been found for chaotic dynamic cardiac systems, making it possible to quantify the differences between normal and pathological cardiac dynamics.
120 electrocardiographic records were analyzed, 40 corresponded to subjects within the limits of normality and 80 with different pathologies. For each holter the attractors generated with the data during 18 hours and throughout the dynamics were analyzed. The fractal dimension of the attractor and its spatial occupation were calculated. To these measures was applied the diagnosis mathematical evaluation previously developed, comparing the evaluation for 18 hours and for the whole registry; sensitivity, specificity and Kappa coefficient were finally calculated.
For the normal dynamics, the occupancy spaces in the Kp grid were between 200 and 381 for the evaluation of the whole holter, and between 201 and 384 in the evaluation during 18 hours, showing the closeness in the measurements, which allows that the decrease in the time of the evaluation is consistent, this same proximity was observed for the diseased and acute dynamics.
It was evidenced the clinical applicability in 18 hours of the exponential law in the chaotic cardiac dynamics associated with arrhythmias showing to be useful for the prediction of the evolution towards acute states of the dynamics
已发现混沌动态心脏系统的指数定律，这使得量化正常与病理心脏动力学之间的差异成为可能。
分析了120份心电图记录，其中40份对应正常范围内的受试者，80份对应不同病理情况的受试者。对每份动态心电图，分析了在18小时内及整个动态过程中利用数据生成的吸引子。计算了吸引子的分形维数及其空间占有率。对这些测量结果应用了先前开发的诊断数学评估方法，比较了18小时评估和整个记录的评估结果；最终计算了敏感性、特异性和kappa系数。
对于正常动力学，在整个动态心电图评估中，Kp网格中的占用空间在200至381之间，在18小时评估中在201至384之间，测量结果显示出紧密性，这表明评估时间的减少是一致的，在患病和急性动力学中也观察到了同样的接近性。
已证明与心律失常相关的混沌心脏动力学中指数定律在18小时内具有临床适用性，显示出对预测动力学向急性状态演变有用。
