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人群中男性的自闭症特征与唾液睾酮浓度之间没有关系。

No relationship between autistic traits and salivary testosterone concentrations in men from the general population.

机构信息

Neurocognitive Developmental Unit, School of Psychological Science, University of Western Australia, Perth, Western Australia, Australia.

Telethon Kids Institute, University of Western Australia, Perth, Western Australia, Australia.

出版信息

PLoS One. 2018 Jun 14;13(6):e0198779. doi: 10.1371/journal.pone.0198779. eCollection 2018.

Abstract

It is suggested that testosterone may play a part in the higher prevalence of Autism Spectrum Disorder (ASD) in males compared to females. Previous studies have reported elevated postnatal testosterone levels in children and women with ASD but not in men. We compared levels of salivary testosterone across 67 undergraduate males (Mage 19.5 yrs, SD 1.92) selected for low, mid-range and high levels of autistic traits assessed using the Autism-spectrum Quotient. Analyses revealed no significant differences in testosterone concentrations across the three groups. The current data add to the increasing evidence for the lack of relationship between autistic traits and postnatal levels of testosterone in men.

摘要

有研究表明,与女性相比,男性自闭症谱系障碍(ASD)的发病率更高,睾丸酮可能在此过程中发挥了一定作用。此前的研究报告称,自闭症谱系障碍儿童和女性的产后睾丸酮水平升高,但男性并非如此。我们比较了 67 名大学生男性(平均年龄 19.5 岁,标准差 1.92)唾液中的睾丸酮水平,这些男性根据自闭症量表评估的自闭症特征,分为低、中、高三个组别。分析结果显示,三组的睾丸酮浓度没有显著差异。目前的数据进一步证明,男性自闭症特征与产后睾丸酮水平之间没有关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/381b/6002020/a7afa855e1d2/pone.0198779.g001.jpg

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