Cheng Xuting, Wang Hong, Yuan Baocheng, Guan Peiyu, Wang Lingyi
School of Public Health and Management, Chongqing Medical University, Research Center for Medicine and Social Development, Innovation Center for Social Risk Governance in Health, Chongqing 400016, China.
Wei Sheng Yan Jiu. 2017 Jul;46(4):557-562.
To study the prevalence and family factors on metabolic syndrome( MS) in children and adolescents for Chongqing City.
Multi-stage cluster sampling was used to recruit 1309 children and adolescents between 10 and 17 years old for physical examination( height, weight, waist circumference and blood pressure), blood biochemical examination( fasting plasma glucose, triglyceride, total cholesterol, high density lipoprotein cholesterol and low density lipoprotein cholesterol)and questionnaire for family factors( breast feeding, delivery mode, birth weight, education of parents, height and weight of parents, family history of hypertension and diabetes, and so on). MS was diagnosed by the definition of metabolic syndrome and prophylaxis and treatment proposal in Chinese children and adolescents.
The prevalence of MS on children and adolescents in Chongqing city was 5. 5%, and among normal weight, overweight, and obese groups were 0. 6%, 13. 8% and 41. 2%, respectively. Univariate analysis showed BMI of father( χ2= 8. 237, P = 0. 016), BMI of mother( χ2= 8. 978, P = 0. 011), occupation of father( χ2= 7. 742, P = 0. 021), occupation of mother( χ2= 6. 578, P = 0. 037) and family history of hypertension( χ~2=7. 684, P = 0. 006) were associated with MS. Logistic regression analysis showed father's overweight( OR = 1. 956, 95% CI 1. 176-3. 254), mother's obesity( OR = 2. 934, 95%CI 1. 230-6. 999) and family history of hypertension( OR = 1. 867, 95% CI 1. 139-3. 059) were risk factors for MS.
The detection rate of MS on children and adolescents in Chongqing city is higher, and the mainly risk family factors are father's overweight, mother's obesity and family history of hypertension.
研究重庆市儿童青少年代谢综合征（MS）的患病率及家庭因素。
采用多阶段整群抽样法，选取1309名10至17岁的儿童青少年进行体格检查（身高、体重、腰围和血压）、血液生化检查（空腹血糖、甘油三酯、总胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇）以及家庭因素问卷调查（母乳喂养、分娩方式、出生体重、父母教育程度、父母身高和体重、高血压和糖尿病家族史等）。根据中国儿童青少年代谢综合征的定义及防治建议诊断MS。
重庆市儿童青少年MS患病率为5.5%，正常体重、超重和肥胖组分别为0.6%、13.8%和41.2%。单因素分析显示，父亲的BMI（χ² = 8.237，P = 0.016）、母亲的BMI（χ² = 8.978，P = 0.011）、父亲的职业（χ² = 7.742，P = 0.021）、母亲的职业（χ² = 6.578，P = 0.037）和高血压家族史（χ² = 7.684，P = 0.006）与MS有关。Logistic回归分析显示，父亲超重（OR = 1.956，95%CI 1.176 - 3.254）、母亲肥胖（OR = 2.934，95%CI 1.230 - 6.999）和高血压家族史（OR = 1.867，95%CI 1.139 - 3.059）是MS的危险因素。
重庆市儿童青少年MS检出率较高，主要的家庭危险因素是父亲超重、母亲肥胖和高血压家族史。
