Zhang Jian, Zhao Ai, Tan Shengjie, Zhao Wenzhi, Wang Yan, Li Ting, Szeto Ignatius Man-Yau, Zhang Yumei
School of Public Health, Peking University, Beijing 100083, China.
Wei Sheng Yan Jiu. 2018 Mar;47(2):212-217.
To assess the differences between anthropometric indices in predicting dyslipidemia in Chinese urban adult population and find optimal cut-off points.
A total of 1615 subjects with information on key variables were enrolled by multistage stratified sampling process from March to July in 2016. Information on sociodemographic characteristics( age, gender, nationality, education and income), and health and disease history of subjects was collected. Height, weight, waist circumference( WC), hip circumference, body fat percentage( % Fat), and fasting lipid profiles were measured for each participant. The receiver operating characteristic( ROC) curve was used to compare the efficacy of the various anthropometric indices to discriminate those with and without dyslipidemia.
Waist-to-height ratio( WHtR) had the largest area under the ROC curve( AUC) for dyslipidemia in women( 0. 744). There weresignificant differences between AUC of WHtR and that of WC( P = 0. 008), body mass index( BMI, P = 0. 004), waist-to-hip ratio( WHR, P = 0. 005), and % Fat( P <0. 001) in pairwise comparisons. Cut-off point for WHtR was 0. 50 for dyslipidemia in urban adult women. Although the AUC for BMI was the highest for dyslipidemia in men, it did not differ significantly from other indices( P all > 0. 05). Cut-off point for BMI was24. 1 kg/m~2 for dyslipidemia in urban adult men.
WHtR and BMI might be optimal indices for dyslipidemia for Chinese urban adult women and men, respectively. Regional and sexual differences should be considered when choosing proper indices.
评估人体测量指标在预测中国城市成年人群血脂异常方面的差异,并找出最佳切点。
2016年3月至7月,通过多阶段分层抽样方法共纳入1615名具有关键变量信息的受试者。收集受试者的社会人口学特征(年龄、性别、国籍、教育程度和收入)以及健康和疾病史。测量每位参与者的身高、体重、腰围(WC)、臀围、体脂百分比(%Fat)和空腹血脂谱。采用受试者工作特征(ROC)曲线比较各种人体测量指标区分血脂异常患者和非血脂异常患者的效能。
腰围身高比(WHtR)在女性血脂异常的ROC曲线下面积(AUC)最大(0.744)。在两两比较中,WHtR的AUC与WC的AUC(P = 0.008)、体重指数(BMI,P = 0.004)、腰臀比(WHR,P = 0.005)和%Fat的AUC(P <0.001)之间存在显著差异。城市成年女性血脂异常的WHtR切点为0.50。虽然男性血脂异常的BMI的AUC最高,但与其他指标相比差异无统计学意义(P均>0.05)。城市成年男性血脂异常的BMI切点为24.1kg/m²。
WHtR和BMI可能分别是中国城市成年女性和男性血脂异常的最佳指标。选择合适指标时应考虑地区和性别差异。