Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota; Division of Cardiovascular Diseases, Department of Medicine, West Virginia University, Morgantown, West Virginia.
Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota. Electronic address: https://twitter.com/noseworthypeter.
J Am Coll Cardiol. 2018 Jun 19;71(24):2790-2801. doi: 10.1016/j.jacc.2018.04.013.
Ischemic stroke in patients with atrial fibrillation is associated with substantial morbidity and mortality. The growing epidemic of atrial fibrillation worldwide has raised concerns about the dire need for effective stroke prevention systems in these patients. Fortunately, the last decade has witnessed a plethora of data on novel stroke prevention methods in patients with nonvalvular atrial fibrillation. However, optimal selection and effective implementation of these preventative strategies require an integrative approach that takes into account not only the available clinical data but also the perspective of each of the stakeholders involved (patient, physician, and society). The goal of this review was to discuss the contemporary issues surrounding stroke prevention in atrial fibrillation from the perspective of these 3 major stakeholders.
房颤患者的缺血性脑卒中与较高的发病率和死亡率相关。全球范围内房颤发病率的不断上升，使得人们对这些患者中迫切需要有效的卒中预防系统的担忧日益加剧。幸运的是，过去十年中，有关非瓣膜性房颤患者新型卒中预防方法的数据大量涌现。然而，这些预防策略的最佳选择和有效实施需要一种综合方法，不仅要考虑到现有临床数据，还要考虑到每个利益相关者（患者、医生和社会）的观点。本综述的目的是从这三个主要利益相关者的角度讨论房颤卒中预防的当代问题。
