播散性感染导致免疫激活。
Disseminated infection to immune activation.
作者信息
Yeager Jill, Krenzer Barbara
机构信息
Department of Internal Medicine, State University of New York Upstate Medical University, Syracuse, New York.
出版信息
Proc (Bayl Univ Med Cent). 2018 May 16;31(3):345-346. doi: 10.1080/08998280.2018.1465321. eCollection 2018 Jul.
Abstract
A 61-year-old woman with rheumatoid arthritis on chronic immunosuppression presented with fever. Laboratory studies demonstrated multiorgan failure with pancytopenia, elevation in liver function studies, and an elevated ferritin level, with a diagnosis of hemophagocytic lymphohistiocytosis confirmed on bone marrow biopsy. After initial treatment with chemotherapy, fungal blood cultures grew , prompting initiation of antifungal therapy, which resulted in successful treatment of -associated hemophagocytic lymphohistiocytosis.
摘要
一名61岁患有类风湿关节炎且长期接受免疫抑制治疗的女性出现发热症状。实验室检查显示多器官功能衰竭伴全血细胞减少、肝功能检查指标升高以及铁蛋白水平升高，骨髓活检确诊为噬血细胞性淋巴组织细胞增生症。在接受化疗初始治疗后，血培养发现真菌生长，遂开始抗真菌治疗，该治疗成功治愈了相关的噬血细胞性淋巴组织细胞增生症。
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