Zhang Yongfeng, Shi Xuhua, Lu Yuewu
Department of Rheumatology and Immunology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, P.R. China.
Exp Ther Med. 2018 Jun;15(6):5523-5527. doi: 10.3892/etm.2018.6095. Epub 2018 Apr 25.
Panniculitis is a group of heterogeneous disorders characterized by inflammation of the subcutaneous adipose tissue. Panniculitis of breast tissue as the initial manifestation has rarely been reported and is often misdiagnosed. Breast panniculitis may cause substantial morbidity and early diagnosis and treatment are important for the prognosis of the disease. The present study has reported a case of panniculitis with inflammation of the mammary glands as the initial presentation and provided a detailed description of ultrasonography, X-ray, computed tomography, magnetic resonance imaging and other imaging features of breast panniculitis. The treatment and follow-up were also described. Following treatment with systemic corticosteroids combined with methotrexate and thalidomide for 2 months, the breast appeared to be normal without scar formation. The present case report provides a good reference for the future diagnosis and treatment of breast panniculitis.
脂膜炎是一组以皮下脂肪组织炎症为特征的异质性疾病。以乳腺组织脂膜炎为首发表现的情况鲜有报道,且常被误诊。乳腺脂膜炎可能导致严重的发病率,早期诊断和治疗对该疾病的预后很重要。本研究报告了一例以乳腺炎症为首发表现的脂膜炎病例,并详细描述了乳腺脂膜炎的超声、X线、计算机断层扫描、磁共振成像等影像学特征。还介绍了治疗及随访情况。经全身用糖皮质激素联合甲氨蝶呤和沙利度胺治疗2个月后,乳房外观正常,未形成瘢痕。本病例报告为未来乳腺脂膜炎的诊断和治疗提供了良好的参考。