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一名老年男性自发性冠状动脉夹层的不寻常表现。

Unusual Presentation of Spontaneous Coronary Artery Dissection in an Older Male.

作者信息

Joea Rajveer, Strube Sarah J, Zynda Todd K

机构信息

Department of Internal Medicine, St Mary Medical Center, Long Beach, CA 90813, USA.

Health Science, St Mary Medical Center, Long Beach, CA 90813, USA.

出版信息

Cardiol Res. 2018 Jun;9(3):191-194. doi: 10.14740/cr717w. Epub 2018 Jun 6.

Abstract

Spontaneous coronary artery dissection (SCAD) is a variant of acute coronary syndrome (ACS) that is poorly understood. SCAD has been linked to fibromuscular dysplasia (FMD), connective tissue disease (CTD), pregnancy and hormonal imbalance, systemic inflammatory conditions (e.g. IBD, vasculitis), and coronary artery vasospasm rather than traditional cardiac risk factors. Symptomology generally accompanying SCAD is indistinguishable from ACS making the timely recognition and diagnosis vital for prompt treatment. Management of SCAD is not well defined given the absence of guidelines; conservative therapy with or without invasive intervention is assessed on a case-by-case basis. In this article, we report the case of a 62-year-old male, who presented with chest pain and dyspnea on exertion and was found to have an elevated troponin-I level and corresponding electrocardiogram (EKG) findings, subsequently diagnosed with a non-ST elevation myocardial infarction (NSTEMI). Coronary angiography revealed a distal right coronary artery (RCA) dissection, which was confirmed later with intravascular ultrasound (IVUS). The patient then underwent percutaneous coronary intervention (PCI) followed by stenting of the distal RCA and was discharged on optimal medical therapy. Herein, we report a case of SCAD in an otherwise healthy male with chest pain at rest and with mild exertion without conventional cardiac risk factors.

摘要

自发性冠状动脉夹层(SCAD)是一种急性冠状动脉综合征(ACS)的变体,目前人们对其了解甚少。SCAD与纤维肌发育不良(FMD)、结缔组织病(CTD)、妊娠和激素失衡、全身性炎症性疾病(如炎症性肠病、血管炎)以及冠状动脉血管痉挛有关,而非传统的心脏危险因素。SCAD通常伴随的症状与ACS难以区分,因此及时识别和诊断对于及时治疗至关重要。鉴于缺乏相关指南,SCAD的治疗方法尚无明确界定;对于是否采用侵入性干预的保守治疗需逐案评估。在本文中,我们报告了一例62岁男性病例,该患者因胸痛和劳力性呼吸困难就诊,肌钙蛋白I水平升高且有相应的心电图(EKG)表现,随后被诊断为非ST段抬高型心肌梗死(NSTEMI)。冠状动脉造影显示右冠状动脉(RCA)远端夹层,随后血管内超声(IVUS)证实了这一情况。该患者随后接受了经皮冠状动脉介入治疗(PCI),接着对RCA远端进行了支架置入,并在接受最佳药物治疗后出院。在此,我们报告一例在无传统心脏危险因素的情况下,静息及轻度劳力时出现胸痛的健康男性SCAD病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d08e/5997434/748d192cce8c/cr-09-191-g001.jpg

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