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使用机械血栓切除术装置治疗原位肝移植术后早期肝动脉血栓形成。

Use of a mechanical thrombectomy device to treat early hepatic artery thrombosis after orthotopic liver transplant.

作者信息

Meek James C, McDougal Jonathan S, Borja-Cacho Daniel, Meek Mary E

机构信息

Department of Radiology, College of Medicine, University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 556, Little Rock, AR 72205, USA.

College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

出版信息

Radiol Case Rep. 2017 Dec 28;13(2):522-526. doi: 10.1016/j.radcr.2017.12.007. eCollection 2018 Apr.

DOI:10.1016/j.radcr.2017.12.007
PMID:29904504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6000183/
Abstract

Hepatic artery thrombosis (HAT) is a major cause of morbidity and mortality after orthotopic liver transplantation, occurring in 5% of cases (Piardi et al, 2016). HAT is the second main cause of graft loss after primary nonfunction, the leading cause of graft failure in the immediate postoperative period (<1 month), and is associated with a mortality rate of up to 60% without intervention (Piardi et al, 2016; Pareja et al., 2010; Crossin et al., 2003). Although retransplantation is the preferred therapy, the limited availability of donor organs can necessitate urgent, alternative treatment. These patients present physicians with an often-severe clinical picture, which requires consideration of endovascular approaches as opposed to the more traditional, invasive surgical interventions. The following case study presents a novel mechanical therapy that uses an endovascular approach for revascularization-a stent retriever device.

摘要

肝动脉血栓形成(HAT)是原位肝移植术后发病和死亡的主要原因,发生率为5%(Piardi等人,2016年)。HAT是原发性无功能后移植物丢失的第二大主要原因,是术后早期(<1个月)移植物失败的主要原因,并且在未经干预的情况下死亡率高达60%(Piardi等人,2016年;Pareja等人,2010年;Crossin等人,2003年)。尽管再次移植是首选治疗方法,但供体器官的有限可用性可能需要紧急的替代治疗。这些患者给医生带来的往往是严重的临床情况,这需要考虑采用血管内方法,而不是更传统的侵入性手术干预。以下案例研究介绍了一种使用血管内方法进行血管重建的新型机械疗法——支架取栓装置。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/7a3c738aab5e/radcr416-fig-0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/a1a4cc596dc5/radcr416-fig-0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/8ef43c9c29c7/radcr416-fig-0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/c708b394c969/radcr416-fig-0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/1936b2a50ac8/radcr416-fig-0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/7a3c738aab5e/radcr416-fig-0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/a1a4cc596dc5/radcr416-fig-0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/8ef43c9c29c7/radcr416-fig-0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/c708b394c969/radcr416-fig-0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/1936b2a50ac8/radcr416-fig-0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8966/6000183/7a3c738aab5e/radcr416-fig-0005.jpg

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Stroke. 2016 Mar;47(3):798-806. doi: 10.1161/STROKEAHA.115.012360.
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Stent Retrievers for the Treatment of Acute Ischemic Stroke: A Systematic Review and Meta-analysis of Randomized Clinical Trials.
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JAMA Neurol. 2016 Mar;73(3):275-81. doi: 10.1001/jamaneurol.2015.4441.
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Vascular complications following liver transplantation: A literature review of advances in 2015.肝移植后的血管并发症:2015年进展的文献综述
World J Hepatol. 2016 Jan 8;8(1):36-57. doi: 10.4254/wjh.v8.i1.36.
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Endovascular vs medical management of acute ischemic stroke.急性缺血性卒中的血管内治疗与药物治疗
Neurology. 2015 Dec 1;85(22):1980-90. doi: 10.1212/WNL.0000000000002176. Epub 2015 Nov 4.
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