美国成年人尿液中镉与 QRS-T 角之间的关系。
Association Between Urinary Cadmium and QRS|T Angle Among Adults in the United States.
机构信息
Department of Epidemiology, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas (Ms Thapa, Ms Delhey, Ms Jin, Dr Delongchamp, Dr Faramawi); Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas (Dr Abouelenein, Dr Delongchamp, Dr Faramawi); and Department of Preventive Medicine and Epidemiology, National Liver Institute, Menofiya University, Shebin Elkom, Egypt (Dr Morad).
出版信息
J Occup Environ Med. 2018 Aug;60(8):e412-e415. doi: 10.1097/JOM.0000000000001382.
OBJECTIVE
Cadmium's effect on QRS|T angle has not been studied. An abnormal QRS|T angle deviation may increase the risk for ventricular dysrhythmias.
METHODS
We calculated the orientation of spatial QRS|T angle using QRS and T amplitudes of leads V2, V5, V6, and AVF from the National Health and Nutritional Examination Survey III. Cadmium concentration was measured in urine. We fit weighted unadjusted and adjusted logistic regressions to calculate odds ratios and their corresponding 95% confidence intervals.
RESULTS
A unit increase in the logarithm of urinary cadmium increased the odds of QRS|T angle deviation by 30% [1.30 (1.01 to 1.61)].
CONCLUSIONS
Cadmium exposure was associated with an abnormal QRS|T angle in women but not in men. Women exposed to cadmium should be periodically evaluated to detect QRS|T angle deviation, which can predispose them to ventricular dysrhythmias.
目的
镉对 QRS|T 角的影响尚未得到研究。异常的 QRS|T 角偏差可能会增加室性心律失常的风险。
方法
我们使用来自国家健康和营养检查调查 III 的导联 V2、V5、V6 和 AVF 的 QRS 和 T 振幅计算了空间 QRS|T 角的方向。尿液中的镉浓度进行了测量。我们拟合了加权未调整和调整后的逻辑回归来计算比值比及其相应的 95%置信区间。
结果
尿镉对数每增加一个单位，QRS|T 角偏差的几率增加 30%[1.30（1.01 至 1.61）]。
结论
镉暴露与女性而非男性的异常 QRS|T 角有关。暴露于镉的女性应定期评估以检测 QRS|T 角偏差，这可能使她们容易发生室性心律失常。
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