Mitkovic Voncina Marija, Kosutic Zeljka, Pesic Danilo, Todorovic Dejan, Peulic Aleksandar, Lazarevic Milica, Rakovic Dobroslavic Ivana, Djuric Mina, Bradic Zagorka, Pejovic Milovancevic Milica, Gotlib Dorothy, Lecic Tosevski Dusica
Clinic for Children and Adolescents, Institute of Mental Health.
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan.
J Nerv Ment Dis. 2018 Jul;206(7):537-543. doi: 10.1097/NMD.0000000000000839.
There is an ongoing debate on the relationship between depression and anxiety, but data on similarities and differences in their predictor profiles are scarce. The aim of our study was to compare family and personality predictors of these disorders among 220 "emerging adults." As such, two clinical groups with noncomorbid depressive and anxiety disorders, and one healthy control group were assessed by sociodemographic questionnaires, Structured Clinical Interview for DSM-IV Disorders and NEO Personality Inventory, Revised. We found significant overlap in family and personality risk profiles, with increasing effect size for predictors common to anxiety and depression when the categories "no disorder-anxiety disorder-depressive disorder" were considered as existing along a continuum. Among the contributing factors we assessed, family psychiatric history, family structure and conflicts with parents were more significant than personality traits. Our study indicates that emerging adults may be more vulnerable to depression than anxiety in the presence of family and personality risk factors.
关于抑郁症与焦虑症之间的关系，目前仍存在争议，但关于它们预测因素概况异同的数据却很匮乏。我们研究的目的是比较220名“新兴成年人”中这两种疾病的家庭和人格预测因素。因此，通过社会人口学问卷、《精神疾病诊断与统计手册》第四版障碍的结构化临床访谈以及修订后的大五人格量表对两个患有非共病抑郁和焦虑症的临床组以及一个健康对照组进行了评估。我们发现家庭和人格风险概况存在显著重叠，当将“无疾病-焦虑症-抑郁症”类别视为沿连续体存在时，焦虑症和抑郁症共有的预测因素的效应量不断增加。在我们评估的影响因素中，家族精神病史、家庭结构以及与父母的冲突比人格特质更为显著。我们的研究表明，在存在家庭和人格风险因素的情况下，新兴成年人可能更容易患抑郁症而非焦虑症。
