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Short term regulation of acyl CoA: cholesterol acyl transferase (ACAT) activity in the regenerating and perinatal liver.

作者信息

Bruscalupi G, Leoni S, Mangiantini M T, Piemonte F, Spagnuolo S, Trentalance A

出版信息

Biosci Rep. 1985 Mar;5(3):237-42. doi: 10.1007/BF01119593.

DOI:10.1007/BF01119593
PMID:2990593
Abstract

Acyl coenzyme A : cholesterol acyltransferase (ACAT), the enzyme catalyzing the hepatic cholesterol esterification, could be involved in the modified availability of cholesterol detectable in proliferating systems. While no significant variations are detectable in the regenerating liver, the modified ACAT activity during liver development and its differential sensitivity to the in vitro stimulation of modulatory systems suggest an involvement of the enzyme in this proliferating process.

摘要

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