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泰国多中心大学外科重症监护病房心脏骤停发生率及相关因素研究(泰国外科重症监护病房研究)

Incidence of Cardiac Arrest and Related Factors in a Multi-Center Thai University-Based Surgical Intensive Care Units Study (THAI-SICU Study).

作者信息

Chanthawong Sarinya, Chau-In Waraporn, Pipanmekaporn Tanyong, Chittawatanarat Kaweesak, Kongsayreepong Suneerat, Rojanapithayakorn Nonthida

出版信息

J Med Assoc Thai. 2016 Sep;99 Suppl 6:S91-S99.

Abstract

OBJECTIVE

To describe the incidences, outcomes and determine the risk factor(s) of cardiac arrest in surgical intensive care unit (SICU).

MATERIAL AND METHOD

We collected data between April 2011 and January 2013. The case record form (CRF) included the CRF 1 (admission, daily screening and discharge data) and the CRF 2 for cardiac arrest events. The patients were followed-up until discharge from SICU or for up to 28 days after admission in SICU.

RESULTS

The incidence of cardiac arrest in SICU was 226 in 4,652 patients (4.9%). The APACHE II score at the day with cardiac arrest were 24.1. Initial monitor rhythm during cardiac was asystole (35.4%), bradycardia (22.6%) and pulseless electrical activity (14.6%). The main cause was poor patient condition before admission (51.3%). Most of the cardiac arrest patients (73.9%) had antecedents within 24 hour and the most common antecedents were hypotension, metabolic disturbances and sepsis and/or septic shock. The overall return of spontaneous circulation rate was 23.5%. At hospital discharge, the mortality rate (91.6%) was statistically different between the cardiac arrest and non-cardiac arrest group (p<0.001). The Acute Physiologic and Chronic Health Evaluation II score (APACHE II score) (Odds ratio, (OR 1.15, 95% CI 1.11-1.19, p<0.001), Sequential Organ Failure Assessment score (SOFA score) (OR 1.12, 95% CI 1.03-1.20, p = 0.005) and American Society of Anesthesiologists physical status physical status (ASA PS) ≥3 (OR 2.32, 95% CI 1.33-4.04, p = 0.003) were significantly risk factors for cardiac arrest.

CONCLUSION

Cardiac arrest in the SICU was uncommon. Initial non-shockable rhythms were common and mostly had antecedents before cardiac arrest. The APACHE II score, SOFA score and ASA PS ≥3 were independent risk factors for cardiac arrest in SICU.

摘要

目的

描述外科重症监护病房(SICU)中心脏骤停的发生率、结局并确定其危险因素。

材料与方法

我们收集了2011年4月至2013年1月期间的数据。病例记录表(CRF)包括CRF 1(入院、每日筛查和出院数据)以及用于心脏骤停事件的CRF 2。对患者进行随访,直至其从SICU出院或在入住SICU后长达28天。

结果

SICU中心脏骤停的发生率为4652例患者中有226例(4.9%)。心脏骤停当天的急性生理与慢性健康状况评分系统(APACHE II)评分为24.1。心脏骤停期间的初始监测心律为心脏停搏(35.4%)、心动过缓(22.6%)和无脉电活动(14.6%)。主要原因是入院前患者状况较差(51.3%)。大多数心脏骤停患者(73.9%)在24小时内有前驱症状,最常见的前驱症状是低血压、代谢紊乱以及脓毒症和/或脓毒性休克。自主循环恢复率总体为23.5%。在出院时,心脏骤停组和非心脏骤停组的死亡率(91.6%)在统计学上存在差异(p<0.001)。急性生理与慢性健康状况评分系统II评分(APACHE II评分)(优势比,(OR 1.15,95%置信区间1.11 - 1.19,p<0.001)、序贯器官衰竭评估评分(SOFA评分)(OR 1.12,95%置信区间1.03 - 1.20,p = 0.005)以及美国麻醉医师协会身体状况(ASA PS)≥3(OR 2.32,95%置信区间1.33 - 4.04,p = 0.

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