Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.
Am J Perinatol. 2018 Dec;35(14):1419-1422. doi: 10.1055/s-0038-1660837. Epub 2018 Jun 15.
We conducted a detailed survey to identify medication safety practices among a large network of United States neonatal intensive care units (NICUs).
We created a 53-question survey to assess 300 U.S. NICU's demographics, medication safety practices, adverse drug event (ADE) reporting, and ADE response plans.
Among the 164 (55%) NICUs that responded to the survey, more than 85% adhered to practices including use of electronic health records, computerized physician order entry, and clinical decision support; fewer reported adopting barcoding, formal safety surveys, and formal culture training; 137 of 164 (84%) developed at least one NICU-specific order-set with a median of 10 order-sets.
Among our survey of 164 NICUs, we found that many safety practices remain unused. Understanding safety practice variation is critical to prevent ADEs and other negative infant outcomes. Future efforts should focus on linking safety practices identified from our survey with ADEs and infant outcomes.
我们对美国新生儿重症监护病房（NICU）的大量网络进行了详细调查，以确定药物安全实践情况。
我们创建了一个包含 53 个问题的调查，以评估 300 家美国 NICU 的人口统计学特征、药物安全实践、药物不良事件（ADE）报告和 ADE 应对计划。
在对调查做出回应的 164 家 NICU 中，超过 85%的机构遵守包括使用电子病历、计算机化医嘱录入和临床决策支持在内的实践；但较少的机构报告采用了条形码、正式安全调查和正式文化培训；164 家 NICU 中有 137 家（84%）制定了至少一种特定于 NICU 的医嘱集，中位数为 10 个医嘱集。
在对 164 家 NICU 的调查中，我们发现许多安全实践仍未得到应用。了解安全实践差异对于预防 ADE 和其他不良婴儿结局至关重要。未来的努力应侧重于将我们从调查中确定的安全实践与 ADE 和婴儿结局联系起来。
