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监测未成熟脑的脑氧合:一种神经保护策略?

Monitoring cerebral oxygenation of the immature brain: a neuroprotective strategy?

机构信息

Department of Neonatology, University Medical Center Utrecht, Utrecht, The Netherlands.

Division of Neonatal-Perinatal Medicine, Stony Brook Children's Hospital, Stony Brook, New York, USA.

出版信息

Pediatr Res. 2018 Aug;84(2):159-164. doi: 10.1038/s41390-018-0026-8. Epub 2018 Aug 16.

DOI:10.1038/s41390-018-0026-8
PMID:29907853
Abstract

Monitoring of cerebral oxygenation (rScO) with near-infrared spectroscopy (NIRS) is a feasible noninvasive bedside technique in the NICU. This review discusses the possible neuroprotective role of "pattern recognition" of NIRS-derived rScO in preterm neonates with regard to the prevention of severe intraventricular hemorrhage and hypoxia/hyperoxia-related white matter injury. This neuroprotective role of rScO monitoring is discussed as a modality to aid in the early detection of cerebral oxygenation conditions predisposing to these complications. Practical guidelines are provided concerning management of abnormal rScO patterns as well as a brief discussion concerning the need for international consensus and the legal aspects associated with the introduction of a new NICU bedside monitoring strategy.

摘要

使用近红外光谱(NIRS)监测脑氧合(rScO)是新生儿重症监护病房(NICU)中一种可行的非侵入性床边技术。这篇综述讨论了早产儿中 NIRS 衍生的 rScO 的“模式识别”可能具有神经保护作用,以预防严重的脑室出血和与缺氧/高氧相关的脑白质损伤。rScO 监测的这种神经保护作用被讨论为一种辅助手段,以帮助早期发现导致这些并发症的脑氧合状态。本文还提供了有关管理异常 rScO 模式的实用指南,并简要讨论了引入新的 NICU 床边监测策略所需的国际共识和法律方面。

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