Fawcett H D, Sayle B A, Winsett M Z
Clin Nucl Med. 1985 Jun;10(6):410-2. doi: 10.1097/00003072-198506000-00006.
Twenty-three patients with hepatic cirrhosis and focal defects on Tc-99m sulfur colloid (SC) scintigrams were restudied with In-111 chloride to determine if indium localization in the focal defect is indicative of a hepatoma. Seven of eight patients with proven hepatomas had positive studies; however, six of 15 patients without hepatomas also had studies interpreted as positive. Thus, In-111 chloride is highly sensitive for the detection of hepatomas, and a negative indium study would militate against this diagnosis. The high false-positive rate found may be due to technical factors rather than a lack of specificity of localization; the experience of others seems to support this impression. At present, In-111 chloride scintigraphy for focal hepatic defects appears to be useful in ruling out hepatoma.
对23例肝硬化且Tc-99m硫胶体（SC）闪烁扫描显示有局灶性缺损的患者，用氯化铟-111进行再次研究，以确定局灶性缺损处铟的定位是否提示肝癌。8例经证实患有肝癌的患者中有7例检查结果呈阳性；然而，15例无肝癌的患者中有6例的检查结果也被判定为阳性。因此，氯化铟-111对肝癌的检测高度敏感，铟检查结果为阴性则不利于该诊断。所发现的高假阳性率可能是由于技术因素而非定位缺乏特异性；其他人的经验似乎支持这一观点。目前，氯化铟-111闪烁扫描用于肝局灶性缺损似乎有助于排除肝癌。
