State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550081, China; University of Chinese Academy of Sciences, Beijing 100049, China.
State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550081, China.
J Environ Sci (China). 2018 Jun;68:185-193. doi: 10.1016/j.jes.2017.10.008. Epub 2017 Oct 23.
Rice consumption can be a major pathway for mercury (Hg) exposure, which can cause health hazards to Chinese residents. To accurately assess the potential health risks, the bioaccessibility of Hg in rice samples collected at background and Hg-contamination sites was examined using four in vitro methods. The results showed that <50% of the total mercury (THg) was bioaccessible in the studied rice samples. The THg bioaccessibility in the rice samples collected at the Hg-contaminated site was higher than that observed at the background area. The bioaccessibility of arsenic (As) and cadmium (Cd) was also evaluated for comparison of the four in vitro methods used in this study. The Physiologically Based Extraction Test was found to be the most accurate method based on the consistency of the results compared to those reported in previous studies. The estimated daily intakes of THg via rice consumption using the bioaccessibility data were found to meet the recommendation value set by the JECFA and the WHO in both sites. However, the potential health risk was not negligible at the Hg-contaminated sites, due to the high THg concentration and bioaccessibility in the rice samples.
大米消费可能是汞（Hg）暴露的主要途径，这可能对中国居民的健康造成危害。为了准确评估潜在的健康风险，使用四种体外方法检测了在背景和汞污染地区采集的大米样品中汞的生物可给性。结果表明，在所研究的大米样品中，只有不到 50%的总汞（THg）是生物可利用的。在汞污染地区采集的大米样品中，THg 的生物可给性高于在背景地区观察到的水平。还评估了砷（As）和镉（Cd）的生物可给性，以比较本研究中使用的四种体外方法。基于与先前研究报告结果的一致性，生理相关提取试验被认为是最准确的方法。根据生物利用度数据，通过食用大米摄入的 THg 估计日摄入量在两个地区均符合 JECFA 和世界卫生组织设定的推荐值。然而，由于大米样品中 THg 浓度和生物可给性较高，在汞污染地区仍存在不可忽视的潜在健康风险。
