Liu Zequn, Han Jin, Fu Fang, Liu H S, He Qiu-Ming, Zhong Wei, Wang Hongying, Yang Xin, Li Dongzhi, Liao Can
Guangzhou Medical University, Guangdong, 510182, PR China; Department of Prenatal Diagnostic Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong, 510623, PR China.
Department of Prenatal Diagnostic Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong, 510623, PR China.
Eur J Obstet Gynecol Reprod Biol. 2018 Sep;228:76-81. doi: 10.1016/j.ejogrb.2018.05.039. Epub 2018 Jun 6.
The aim of this study was to make an accurate diagnosis of pyriform sinus fistula (PSF) for prenatal diagnosis.
Medical records were reviewed for all 35 pyriform sinus fistula patients presenting between 2011 and 2017. Ultrasonography (US), fetal magnetic resonance imaging (MRI) and karyotyping were offered during gestation, while computer tomography (CT) and barium esophagography were performed after birth.
Patients included 21 males (60%) and 14 females (40%) with a sex ratio of 1.5:1. The lesion was located on the left side in 32 (91.4%) cases, the right side in 2 (5.7%), and was bilateral (2.8%) in only one case. The sensitivity of CT, MRI, ultrasonography and barium esophagography were 100% (35/35), 69.2% (9/13), 22.9% (8/35), and 80% (20/25), respectively. If the diagnosis was correct, there was almost no recurrence after treatment. Karyotype analysis of all fetuses was normal.
Pyriform sinus fistula is more commonly seen in the left side. Compared with ultrasonography, MRI has more advantages in prenatal diagnosis, and it is more accurate in postpartum CT examination. The outcome of children with pyriform sinus fistula may be guarded when it correct diagnosis.
本研究旨在对梨状窝瘘（PSF）进行准确诊断以用于产前诊断。
回顾了2011年至2017年间就诊的35例梨状窝瘘患者的病历。孕期进行超声检查（US）、胎儿磁共振成像（MRI）和核型分析，出生后进行计算机断层扫描（CT）和食管钡餐造影。
患者包括21名男性（60%）和14名女性（40%），性别比为1.5:1。病变位于左侧32例（91.4%），右侧2例（5.7%），仅1例为双侧（2.8%）。CT、MRI、超声检查和食管钡餐造影的敏感性分别为100%（35/35）、69.2%（9/13）、22.9%（8/35）和80%（20/25）。若诊断正确，治疗后几乎无复发。所有胎儿的核型分析均正常。
梨状窝瘘在左侧更为常见。与超声检查相比，MRI在产前诊断中具有更多优势，产后CT检查更准确。梨状窝瘘患儿若诊断正确，预后可能较好。
