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以严重产后瘙痒为表现的格雷夫斯病。

Graves' disease presenting as severe postpartum pruritus.

作者信息

Carpenter Rachel Marinch, Wongward Jessica

机构信息

Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Family Medicine, Saint Joseph Hospital Family Medicine Residency, Denver, Colorado, USA.

出版信息

BMJ Case Rep. 2018 Jun 15;2018:bcr-2018-225347. doi: 10.1136/bcr-2018-225347.

DOI:10.1136/bcr-2018-225347
PMID:29909393
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6011479/
Abstract

A 39-year-old multigravida woman presented 3 weeks postpartum with worsening generalised pruritus without primary rash. Workup was significant for cholestasis and undiagnosed Graves' disease. She began to have symptomatic relief after starting methimazole, and liver function tests normalised as she became euthyroid.

摘要

一名39岁的经产妇在产后3周出现全身瘙痒加重，但无原发性皮疹。检查发现有胆汁淤积和未确诊的格雷夫斯病。开始服用甲巯咪唑后她的症状开始缓解，随着甲状腺功能恢复正常，肝功能检查也恢复正常。

相似文献

1
Graves' disease presenting as severe postpartum pruritus.以严重产后瘙痒为表现的格雷夫斯病。
BMJ Case Rep. 2018 Jun 15;2018:bcr-2018-225347. doi: 10.1136/bcr-2018-225347.
2
Graves' disease presenting with severe cholestasis.格雷夫斯病致严重胆汁淤积。
Thyroid. 2012 Apr;22(4):437-9. doi: 10.1089/thy.2011.0267.
3
Effects of chronic iodine administration on thyroid status in euthyroid subjects previously treated with antithyroid drugs for Graves' hyperthyroidism.慢性碘给药对既往因格雷夫斯甲亢接受抗甲状腺药物治疗的甲状腺功能正常受试者甲状腺状态的影响。
J Clin Endocrinol Metab. 1993 Apr;76(4):928-32. doi: 10.1210/jcem.76.4.7682562.
4
New-onset Graves' disease in the postpartum period.产后新发 Graves 病。
J Midwifery Womens Health. 2013 Mar-Apr;58(2):211-4. doi: 10.1111/jmwh.12016.
5
Persistent Graves' hyperthyroidism despite rapid negative conversion of thyroid-stimulating hormone-binding inhibitory immunoglobulin assay results: a case report.尽管促甲状腺激素结合抑制性免疫球蛋白检测结果迅速转阴，但仍存在持续性格雷夫斯甲亢：一例报告
J Med Case Rep. 2017 Feb 6;11(1):32. doi: 10.1186/s13256-017-1214-6.
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Changes of serum cytokines in hyperthyroid Graves' disease patients at diagnosis and during methimazole treatment.诊断时和甲巯咪唑治疗期间甲状腺功能亢进 Graves 病患者血清细胞因子的变化。
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A Case of Graves' Disease Accompanied with Acute Hepatitis A Virus Infection.1例格雷夫斯病合并甲型肝炎病毒急性感染
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Intern Med. 2004 Apr;43(4):306-9. doi: 10.2169/internalmedicine.43.306.

本文引用的文献

1
Rescue of Graves Thyrotoxicosis-Induced Cholestatic Liver Disease Without Antithyroid Drugs: A Case Report.未使用抗甲状腺药物救治格雷夫斯甲状腺毒症所致胆汁淤积性肝病：一例报告
J Endocr Soc. 2017 Feb 15;1(3):231-236. doi: 10.1210/js.2016-1065. eCollection 2017 Mar 1.
2
Risk factors of hepatic dysfunction in patients with Graves' hyperthyroidism and the efficacy of 131iodine treatment.格雷夫斯甲亢患者肝功能障碍的危险因素及¹³¹碘治疗的疗效
Medicine (Baltimore). 2017 Feb;96(5):e6035. doi: 10.1097/MD.0000000000006035.
3
Neonatal Cholestasis Caused by Undiagnosed Maternal Graves' Disease.未诊断出的母体格雷夫斯病导致的新生儿胆汁淤积症。
ACG Case Rep J. 2014 Oct 10;2(1):58-60. doi: 10.14309/crj.2014.85. eCollection 2014 Oct.
4
Risk factors of hyperthyroidism with hepatic function injury: a 4-year retrospective study.甲状腺功能亢进合并肝功能损伤的危险因素：一项4年回顾性研究。
Horm Metab Res. 2015 Mar;47(3):209-13. doi: 10.1055/s-0034-1375690. Epub 2014 May 27.
5
Hepatic dysfunction in hospitalized patients with acute thyrotoxicosis: a decade of experience.急性甲状腺毒症住院患者的肝功能障碍：十年经验
ISRN Endocrinol. 2012;2012:325092. doi: 10.5402/2012/325092. Epub 2012 Nov 29.
6
An unusual case of hyperthyroidism associated with jaundice and hypercalcaemia.一例罕见的伴有黄疸和高钙血症的甲状腺功能亢进病例。
BMJ Case Rep. 2012 May 8;2012:bcr1120115076. doi: 10.1136/bcr.11.2011.5076.
7
Graves' disease presenting with severe cholestasis.格雷夫斯病致严重胆汁淤积。
Thyroid. 2012 Apr;22(4):437-9. doi: 10.1089/thy.2011.0267.
8
Increased incidence of hypothyroidism in primary biliary cirrhosis.原发性胆汁性肝硬化患者甲状腺功能减退症发病率增加。
Dig Dis Sci. 1983 Nov;28(11):971-5. doi: 10.1007/BF01311724.
9
Thyroid hormones and the hepatic handling of bilirubin. I. Effects of hypothyroidism and hyperthyroidism on the hepatic transport of bilirubin mono- and diconjugates in the Wistar rat.甲状腺激素与肝脏对胆红素的处理。I. 甲状腺功能减退和亢进对Wistar大鼠肝脏胆红素单葡萄糖醛酸苷和双葡萄糖醛酸苷转运的影响。
Hepatology. 1989 Feb;9(2):314-21. doi: 10.1002/hep.1840090225.