Baheti Gaurav, Mehta Varshil, Ramchandani Menka, Ghosh Gopal Chandra
Department of Internal Medicine, Seven Hills Hospital, Mumbai, Maharashtra, India.
Department of Internal Medicine, MGM Medical College Kamothe, Navi Mumbai, Maharashtra, India.
BMJ Case Rep. 2018 Jun 15;2018:bcr-2018-225463. doi: 10.1136/bcr-2018-225463.
The clinical profile and presentation of patients with dengue fever may differ from asymptomatic infection to the dreadful complications like dengue shock syndrome. However, neurological complications are very rare. Dengue encephalitis occurs by a direct involvement of central nervous system by the dengue virus which is an extremely rare complication. A 33-year-old man presented with fever, vomiting and severe headache. He had one episode of generalised tonic-clonic seizure followed by an altered sensorium on the day of admission to the hospital. The diagnosis of dengue fever was confirmed by dengue serology (IgM) and (NS1) antigen assay. MRI brain was suggestive of encephalitis. Thus, the patient was treated symptomatically and discharged in stable condition with minimal neurological deficit.
登革热患者的临床特征和表现可能各不相同，从无症状感染到登革热休克综合征等可怕并发症都有。然而，神经系统并发症非常罕见。登革热脑炎是由登革热病毒直接侵犯中枢神经系统引起的，这是一种极其罕见的并发症。一名33岁男性出现发热、呕吐和严重头痛。入院当天，他发生了一次全身性强直阵挛性癫痫发作，随后意识改变。登革热血清学（IgM）和（NS1）抗原检测确诊为登革热。脑部MRI提示为脑炎。因此，对该患者进行了对症治疗，出院时病情稳定，仅有轻微神经功能缺损。
