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成功治疗血流动力学不稳定的创伤性脾损伤的非手术管理:英国一家大型创伤中心的 4 年病例系列。

Successful non-operative management of haemodynamically unstable traumatic splenic injuries: 4-year case series in a UK major trauma centre.

机构信息

Intensive Care Unit, Southmead Hospital, Southmead Road, Bristol, BS10 5NB, UK.

出版信息

Eur J Trauma Emerg Surg. 2019 Oct;45(5):933-938. doi: 10.1007/s00068-018-0975-y. Epub 2018 Jun 16.

DOI:10.1007/s00068-018-0975-y
PMID:29909466
Abstract

PURPOSE

Management of traumatic splenic injury may be operative or non-operative (including embolization and conservative management). Traditionally, haemodynamic instability has been an indication for operative intervention. We aimed to report our experience of managing traumatic splenic injury at a regional major trauma centre in the UK over a 4-year period, with a particular focus on the non-operative management (NOM) of haemodynamically unstable patients.

METHODS

All patients with splenic injuries admitted to North Bristol NHS Trust from April 2012 to March 2016 were included. Patients were classified for analyses by injury severity (low or high grade), haemodynamic instability (defined as a reverse shock index < 1) and management category (operative or non-operative).

RESULTS

106 patients were included. Overall 85.8% of patients received NOM: 79.2% conservative and 6.6% interventional radiology. Two patients (2.4%) managed conservatively required further intervention. Haemodynamically stable and unstable patients were equally likely to receive NOM (89.7 and 81.3% respectively, p = 1). All unstable patients with low-grade injuries were managed conservatively and only one (2.7%) required further intervention. Two unstable patients with high-grade injuries (28.6%) underwent NOM successfully.

CONCLUSIONS

These data support the safe application of non-operative management to haemodynamically unstable patients with traumatic splenic injury, particularly in those with low-grade injuries. Additional prospective work is required to define the subgroup of patients for whom this is appropriate and to determine the long-term outcomes of NOM.

摘要

目的

创伤性脾损伤的治疗方法可以是手术或非手术(包括栓塞和保守治疗)。传统上,血流动力学不稳定是手术干预的指征。我们旨在报告在英国一个区域主要创伤中心的 4 年期间处理创伤性脾损伤的经验,特别关注血流动力学不稳定患者的非手术治疗(NOM)。

方法

纳入 2012 年 4 月至 2016 年 3 月期间入住北布里斯托尔国民保健服务信托基金的所有脾损伤患者。根据损伤严重程度(低级别或高级别)、血流动力学不稳定(定义为反向休克指数<1)和治疗类别(手术或非手术)对患者进行分类分析。

结果

共纳入 106 例患者。总体而言,85.8%的患者接受了 NOM:79.2%的患者采用保守治疗,6.6%的患者采用介入放射学治疗。2 名(2.4%)接受保守治疗的患者需要进一步干预。血流动力学稳定和不稳定的患者接受 NOM 的可能性相同(分别为 89.7%和 81.3%,p=1)。所有低级别损伤的血流动力学不稳定患者均接受保守治疗,仅 1 例(2.7%)需要进一步干预。2 例高级别损伤的血流动力学不稳定患者(28.6%)成功接受了 NOM。

结论

这些数据支持安全应用非手术治疗方法处理创伤性脾损伤血流动力学不稳定患者,特别是在低级别损伤患者中。需要进一步的前瞻性研究来确定适合这种治疗方法的患者亚组,并确定 NOM 的长期结果。

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