Persian Gulf and Oman Sea Ecology Research Center, Agricultural Research Education and Extension Organization (AREEO), Iranian Fisheries Sciences Research Institute, Bandar Abbas, Iran.
Department of Marine Biology, Faculty of Marine Science and Technology, University of Hormozgan, P.O. Box 7931674576, Bandar Abbas, Iran.
Appl Microbiol Biotechnol. 2018 Aug;102(16):6847-6863. doi: 10.1007/s00253-018-9156-5. Epub 2018 Jun 16.
The marine ecosystem has been known to be a rich source of novel enzymes. Agarase is a key enzyme that can hydrolyze agar in the marine environment. Marine bacterial agarase has been isolated from various sources, such as sediments, coastal water, and deep sea and from the surface of crustaceans and seaweeds. This review presents an account of the agarase production of marine bacteria. General information about agar, agarase, isolation, and purification of marine bacterial agarases; the biochemical properties of native agarase from marine bacteria; the biochemical properties of recombinant marine bacterial agarases from engineered microorganisms; and the industrial future of marine bacterial agarases is analyzed. With recent biotechnological processes, researchers need novel functional enzymes like agarase from marine resources, such as marine bacteria, that can be used for diverse applications in the biotechnological industry. Marine bacterial agarases might be of significant interest to the industry because they are safe and are a natural source. This review highlights the potential of marine bacteria as important sources of agarase for application in various industries.
海洋生态系统是新型酶的丰富来源。琼脂酶是一种可以水解海洋环境中琼脂的关键酶。已经从各种来源分离到了海洋细菌琼脂酶,如沉积物、沿海水域和深海,以及甲壳类动物和海藻的表面。本综述介绍了海洋细菌琼脂酶的生产情况。概述了琼脂、琼脂酶、海洋细菌琼脂酶的分离和纯化的一般信息;海洋细菌天然琼脂酶的生化特性;来源于工程微生物的重组海洋细菌琼脂酶的生化特性;以及海洋细菌琼脂酶的工业未来。随着最近的生物技术进程,研究人员需要从海洋资源(如海洋细菌)中获得新型功能酶,如琼脂酶,以便在生物技术工业中进行各种应用。由于海洋细菌琼脂酶安全且天然,因此可能引起业界的极大关注。该综述强调了海洋细菌作为琼脂酶在各个行业应用的重要来源的潜力。