Department of Otorhinolaryngology, Head and Neck Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.
Department of Otorhinolaryngology, Head and Neck Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.
Oral Oncol. 2018 Jul;82:176-180. doi: 10.1016/j.oraloncology.2018.05.022. Epub 2018 Jun 1.
The aim of the study was to compare multifocal extracapsular dissection with complete parotidectomy in the treatment of unilateral multifocal cystadenolymphomas of the parotid gland.
The records from all patients treated for unilateral multifocal cystadenolymphomas of the parotid gland at a tertiary referral center between 2000 and 2016 were retrospectively analyzed.
203 patients were included in the study. 96 patients were managed by multifocal extracapsular dissection, 107 patients underwent complete parotidectomy. Metachronous tumors were detected in 7 cases (3.4%) with a significant difference in the occurrence rate between multifocal extracapsular dissection (7/96, 7.3%) and complete parotidectomy (0/107, 0%) (p = 0.004). Permanent facial palsy was significantly more common after complete parotidectomy (21/107, 19.6%) than multifocal extracapsular dissection (2/96, 2.1%) (p = 0.000).
The functional benefit of multifocal extracapsular dissection was counterbalanced by the advantage of complete parotidectomy, in terms of recurrences. Extracapsular dissection is at its limit in cases of multifocal cystadenolymphomas and the indication for it should be thoroughly verified in each and every case.
本研究旨在比较多灶性囊外解剖与腮腺全切除术治疗单侧多灶性囊性腺淋巴瘤的疗效。
回顾性分析 2000 年至 2016 年间，一家三级转诊中心收治的单侧多灶性囊性腺淋巴瘤患者的资料。
共纳入 203 例患者，96 例行多灶性囊外解剖，107 例行腮腺全切除术。7 例（3.4%）患者发生了异时性肿瘤，多灶性囊外解剖（7/96，7.3%）与腮腺全切除术（0/107，0%）的发生率存在显著差异（p=0.004）。完全切除术后发生永久性面瘫的比例明显高于多灶性囊外解剖（21/107，19.6%）（p=0.000）。
多灶性囊外解剖在功能上的获益，被其在复发方面的劣势所抵消。对于多灶性囊性腺淋巴瘤，囊外解剖已经达到了极限，在每一个病例中，都应仔细验证其适应证。
