原发性甲状腺血管肉瘤：系统评价。

Primary thyroid angiosarcoma: A systematic review.

机构信息

Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.

出版信息

Oral Oncol. 2018 Jul;82:48-52. doi: 10.1016/j.oraloncology.2018.05.004. Epub 2018 May 11.

DOI:10.1016/j.oraloncology.2018.05.004

Abstract

Thyroid angiosarcoma (TAS) is rare and represents a very aggressive malignancy. Its rarity is principally linked to two major pitfalls. Firstly, TAS histopathology diagnosis can be difficult; second, the limited clinical experience with this condition can make its management complex. We conducted a detailed systematic review, focusing on the knowledge available regarding TAS etiopathogenesis, treatment options and prognosis. The aim is to present the main TAS characteristics and to summarize the clinical experiences described worldwide, in order to provide a useful clinical tool.

摘要

甲状腺血管肉瘤（TAS）较为罕见，属于侵袭性很强的恶性肿瘤。其罕见性主要与两个主要陷阱相关。首先，TAS 组织病理学诊断可能较为困难；其次，由于该疾病的临床经验有限，其治疗管理较为复杂。我们进行了详细的系统综述，重点关注 TAS 病因发病机制、治疗选择和预后方面的现有知识。目的是呈现 TAS 的主要特征，并总结全世界描述的临床经验，以提供有用的临床工具。