自然绝经和手术绝经中心血管风险的评估
Assessment of Cardiovascular Risk in Natural and Surgical Menopause.
作者信息
Abbas S Zafar, Sangawan Vijayata, Das Asim, Pandey Anil Kumar
机构信息
Radiodiagnosis, ESIC Medical College and Hospital, Faridabad, India.
Obstetrics and Gynecology, BPS Government Medical College for Women, Khanpur Kalan, Sonepat, India.
出版信息
Indian J Endocrinol Metab. 2018 Mar-Apr;22(2):223-228. doi: 10.4103/ijem.IJEM_620_17.
BACKGROUND
Menopause is associated with increased cardiovascular disease (CVD) risk. Arterial stiffness, a biomarker of vascular aging, increases the risk for CVD.
AIMS AND OBJECTIVES
The study was aimed to determine whether menopause is associated with arterial stiffness amongst natural and surgical menopausal women.
MATERIALS AND METHODS
We conducted a cross-sectional study amongst natural postmenopausal women, with Surgical menopause and Premenopausal. Arterial stiffness was measured by Periscopy TM. Large artery stiffness may be an important mechanism by which hysterectomy increases the risk of cardiovascular disease in postmenopausal women.
RESULTS
Carotid femoral pulse wave velocity (cfPWV) and Brachial Ankle Pulse wave velocity (baPWV) were significantly higher in surgical and natural menopause compared to women with Premenopausal group.
背景
绝经与心血管疾病（CVD）风险增加相关。动脉僵硬度作为血管老化的生物标志物，会增加患心血管疾病的风险。
目的
本研究旨在确定绝经与自然绝经和手术绝经女性的动脉僵硬度是否相关。
材料与方法
我们对自然绝经后女性、手术绝经女性和绝经前女性进行了一项横断面研究。通过Periscopy TM测量动脉僵硬度。大动脉僵硬度可能是子宫切除术增加绝经后女性心血管疾病风险的重要机制。
结果
与绝经前组女性相比，手术绝经和自然绝经女性的颈股脉搏波速度（cfPWV）和臂踝脉搏波速度（baPWV）显著更高。
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