Yatavelli Rajini K, Levine Steven N
1 Section of Endocrinology and Metabolism, Department of Internal Medicine, Louisiana State University Health Sciences Center in Shreveport, Shreveport, Louisiana, USA.
Ann Otol Rhinol Laryngol. 2018 Aug;127(8):558-562. doi: 10.1177/0003489418781169. Epub 2018 Jun 17.
Transient hyperthyroidism has been documented following surgical manipulation or direct trauma to the normal thyroid gland. This has best been studied in patients following parathyroidectomy and also reported following trauma to the neck, strangulation, and vigorous palpation of the thyroid gland. It has not previously been reported following a thyroid ultrasound.
We report the case of a 58-year-old euthyroid woman with a large nontoxic multinodular goiter who developed transient hyperthyroidism following an ultrasound of the thyroid gland. She was not treated with anti-thyroid medications.
Two weeks later, her free T3 and free T4 were normal, and 11 weeks after the ultrasound, all thyroid tests, including her TSH, were within the reference range.
We believe this is the first report of a euthyroid individual who developed hyperthyroidism caused by thyroid ultrasonography. We hypothesize that pressure from the ultrasound probe during the examination compressed her large nodules, releasing stored hormone.
手术操作或对正常甲状腺的直接创伤后曾有短暂性甲状腺功能亢进的记录。这在甲状旁腺切除术后的患者中得到了最好的研究,也有在颈部创伤、勒颈和甲状腺强力触诊后出现相关情况的报道。此前甲状腺超声检查后尚未有相关报道。
我们报告了一例58岁甲状腺功能正常的女性,患有巨大非毒性多结节性甲状腺肿,在甲状腺超声检查后出现短暂性甲状腺功能亢进。她未接受抗甲状腺药物治疗。
两周后,她的游离T3和游离T4正常,超声检查11周后,包括促甲状腺激素在内的所有甲状腺检查结果均在参考范围内。
我们认为这是首例甲状腺功能正常个体因甲状腺超声检查而发生甲状腺功能亢进的报告。我们推测,检查过程中超声探头的压力挤压了她的大结节,释放出储存的激素。