Banerjee R K, Bose A K, Chakraborty T K, De S K, Datta A G
J Endocrinol. 1985 Aug;106(2):159-65. doi: 10.1677/joe.0.1060159.
A method has been developed for the isolation of cells, high in iodine uptake and peroxidase activity, from the stomach and submaxillary gland of mice. The isolated cells could produce protein-bound monoiodotyrosine, di-iodotyrosine and an unknown iodocompound. The reactions were catalysed by peroxidase and were sensitive to antithyroid drugs and haemoprotein inhibitors but were insensitive to TSH. In-vitro iodination of stomach or submaxillary soluble proteins with the respective peroxidase yielded similar iodocompounds while thyroxine was produced when thyroglobulin was used instead.
已开发出一种从小鼠胃和颌下腺中分离出碘摄取量高且过氧化物酶活性高的细胞的方法。分离出的细胞可产生蛋白结合单碘酪氨酸、二碘酪氨酸和一种未知碘化合物。这些反应由过氧化物酶催化，对抗甲状腺药物和血红蛋白抑制剂敏感，但对促甲状腺激素不敏感。用相应的过氧化物酶对胃或颌下腺可溶性蛋白进行体外碘化可产生类似的碘化合物，而用甲状腺球蛋白代替时则会产生甲状腺素。
