Sehested M, Barfoed C, Krogdahl A, Bretlau P
J Oral Pathol. 1985 Jul;14(6):459-65. doi: 10.1111/j.1600-0714.1985.tb00517.x.
Presence of lysozyme, lactoferrin, alpha 1-antitrypsin, alpha 1-antichymotrypsin and ferritin was examined by the immunoperoxidase method in 15 consecutive parotid gland tumors as well as in normal parotid gland tissue. Lysozyme and lactoferrin were detected in intercalated duct cells of normal tissue and in the epithelial component of pleomorphic adenomas. alpha 1-antitrypsin, alpha 1-antichymotrypsin and ferritin were found in both epithelial and mesenchymal components of pleomorphic adenomas but not in normal parotid tissue. In the epithelial component of adenolymphoma only alpha 1-antichymotrypsin and lactoferrin were observed. The results would support a tentative histogenetic link between the intercalated duct cell and the epithelial component of the pleomorphic adenoma.
采用免疫过氧化物酶法检测了15例连续性腮腺肿瘤以及正常腮腺组织中溶菌酶、乳铁蛋白、α1-抗胰蛋白酶、α1-抗糜蛋白酶和铁蛋白的存在情况。在正常组织的闰管细胞和多形性腺瘤的上皮成分中检测到了溶菌酶和乳铁蛋白。在多形性腺瘤的上皮和间叶成分中发现了α1-抗胰蛋白酶、α1-抗糜蛋白酶和铁蛋白，但在正常腮腺组织中未发现。在腺淋巴瘤的上皮成分中仅观察到α1-抗糜蛋白酶和乳铁蛋白。这些结果将支持闰管细胞与多形性腺瘤上皮成分之间存在初步组织发生学联系的推测。
