鼻腔耐甲氧西林金黄色葡萄球菌分离株的分子特征，这些分离株在尝试去定植后，对莫匹罗星的耐药率不断上升，并与多药耐药性相关。
Molecular Characterization of Nasal Methicillin-Resistant Staphylococcus aureus Isolates Showing Increasing Prevalence of Mupirocin Resistance and Associated Multidrug Resistance following Attempted Decolonization.
机构信息
Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland
Department of Infection Prevention and Control, Beaumont Hospital, Dublin, Ireland.
出版信息
Antimicrob Agents Chemother. 2018 Aug 27;62(9). doi: 10.1128/AAC.00819-18. Print 2018 Sep.
Abstract
Sequential methicillin-resistant (MRSA) isolates from patients following attempted mupirocin nasal decolonization showed an increase in mupirocin resistance (MR) from 6.6% to 20%. MR isolates from patients who failed decolonization yielded indistinguishable types and carried multiple antimicrobial and antiseptic resistance genes, which may guide infection control and prevention.
摘要
在试图使用莫匹罗星鼻内去定植后，患者的耐甲氧西林金黄色葡萄球菌（MRSA）连续分离株显示出莫匹罗星耐药性（MR）从 6.6%增加到 20%。去定植失败的患者的 MR 分离株产生了无法区分的类型，并携带多种抗菌和防腐剂耐药基因，这可能有助于指导感染控制和预防。
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