Ghadially F N, Block H J
J Submicrosc Cytol. 1985 Jul;17(3):435-42.
A case of oncocytic carcinoid of the lung was studied with the electron microscope. This rare tumour is composed of cells acceptable as neuroendocrine cells, oncocytes and cells of an intermediate morphology. Our studies lead us to believe that this tumour develops by oncocytic transformation of neuroendocrine cells in a carcinoid. Two new findings reported in this study are: 1) the occurrence of filamentous inclusions in mitochondria; and 2) calcified spherules which appear to develop in material secreted by tumour cells.
对一例肺嗜酸细胞性类癌进行了电镜研究。这种罕见的肿瘤由可被视为神经内分泌细胞的细胞、嗜酸细胞及中间形态的细胞组成。我们的研究使我们相信,该肿瘤是由类癌中的神经内分泌细胞嗜酸细胞化生发展而来。本研究报告的两个新发现是:1)线粒体中出现丝状包涵体;2)钙化小球似乎在肿瘤细胞分泌的物质中形成。