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[使用横向旋转扫描仪分别测量密质骨和松质骨密度。使用最小二乘法算法测定桡骨矿物质含量]

[Separate measurements of compact and spongy bone density using a transverse rotation scanner. Determination of mineral content of the radius using a least squares algorithm].

作者信息

Schneider V P, Berger P, Moll E, Reiners C, Börner W

出版信息

Rofo. 1985 Aug;143(2):178-82. doi: 10.1055/s-2008-1052785.

Abstract

The absorption profile of the distal forearm, which depends on bone mineralisation, was measured using a high resolution microcomputer-controlled transverse rotational scanner with a tightly collimated I-125 photon source and a scintillation counter. Reconstruction of the anatomical structures within the measured area occurred in two stages. Subsequently the linear attenuation coefficient for soft tissues, compacta and spongiosa was obtained by a "least-square" algorithm. The absorption coefficient of the compacta and spongiosa provided a measure of bone mineralisation. Correlation between the reconstructed images and the calculated results and measurements was tested by calculation. Ten measurements of a model and of in vivo bones resulted in a coefficient of variation of 1.8% and 3.3% for the compacta and 2.5% and 3.8% for the spongiosa. Relative deviation from the standard varied from +1.3% to -1.0%, depending on mineral content. This new, technically simple procedure for the separate determination of the compacta and spongiosa in the distal radius is useful for the early recognition of changes in bone mineralisation which are usually apparent first in the spongiosa.

摘要

使用配备紧密准直的 I - 125 光子源和闪烁计数器的高分辨率微机控制横向旋转扫描仪,测量了取决于骨矿化的前臂远端的吸收曲线。测量区域内解剖结构的重建分两个阶段进行。随后,通过“最小二乘法”算法获得软组织、密质骨和松质骨的线性衰减系数。密质骨和松质骨的吸收系数提供了骨矿化的一种度量。通过计算测试了重建图像与计算结果及测量值之间的相关性。对一个模型和体内骨骼进行的十次测量结果显示,密质骨的变异系数为 1.8% 和 3.3%,松质骨的变异系数为 2.5% 和 3.8%。相对于标准的相对偏差在 +1.3% 至 -1.0% 之间变化,具体取决于矿物质含量。这种用于单独测定桡骨远端密质骨和松质骨的新技术简单的方法,对于早期识别通常首先在松质骨中出现的骨矿化变化很有用。

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