Uhlenbrock D, Börsch G, Beyer H K, Schmidt G
Rofo. 1985 Aug;143(2):200-7. doi: 10.1055/s-2008-1052790.
We examined 21 patients with focal lesions of the liver. Routinely we used T1 weighted, proton weighted and T2 weighted measurement modes, mainly with repetition times of 1.6 sec and echo delay times of 35 or 120 msec. Using these parameters we can see characteristic changes of the signals of the liver tumours. Cystic lesions usually show a strong decrease of the signal in the T1 weighted images in comparison with the normal liver pattern, in the proton weighted images a weak decrease but also in some cases a weak increase of the signal; in the T2 weighted images they show signals of very great intensity. We can differentiate haemangioma of cystic lesions because of the very strong signal in the proton weighted images in comparison with the normal liver pattern, which we could not see in any other focal liver disease. Metastases and hepatoma produced low signal intensity in the T1 weighted image. The proton weighted and the T2 weighted images show signals with a slightly greater intensity compared with the normal pattern, i.e. a very good possibility to distinguish hepatoma and metastases from cystic lesions or haemangioma. The differentiation from hepatoma and metastases cannot be made with NMR up to now. We are also not able to differentiate the focal nodular hyperplasia (FNH) from metastases. We used a 0.35 T supraconductive magnetic system.
我们检查了21例肝脏局灶性病变患者。常规采用T1加权、质子加权和T2加权测量模式，主要重复时间为1.6秒，回波延迟时间为35或120毫秒。利用这些参数，我们可以看到肝脏肿瘤信号的特征性变化。囊性病变在T1加权图像中与正常肝脏模式相比信号通常明显降低，在质子加权图像中信号轻度降低，但在某些情况下也会轻度升高；在T2加权图像中它们显示出非常高的信号强度。我们可以区分囊性病变的血管瘤，因为与正常肝脏模式相比，质子加权图像中的信号非常强，这在任何其他肝脏局灶性疾病中都看不到。转移瘤和肝癌在T1加权图像中产生低信号强度。质子加权和T2加权图像显示的信号强度比正常模式略高，即很有可能将肝癌和转移瘤与囊性病变或血管瘤区分开来。到目前为止，核磁共振无法区分肝癌和转移瘤。我们也无法将局灶性结节性增生（FNH）与转移瘤区分开来。我们使用的是0.35T超导磁体系统。
