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Postsynaptic blocking of glutamatergic and cholinergic synapses as a common property of Araneidae spider venoms.

作者信息

Usmanov P B, Kalikulov D, Shadyeva N G, Nenilin A B, Tashmukhamedov B A

出版信息

Toxicon. 1985;23(3):528-31. doi: 10.1016/0041-0101(85)90038-8.

DOI:10.1016/0041-0101(85)90038-8
PMID:2992124
Abstract

Venom effects of eight Araneidae spider species were studied using locust and frog neuromuscular junctions. The spider venoms irreversibly blocked miniature excitatory postsynaptic potentials and excitatory postsynaptic potentials of locust neuromuscular junction. The frog miniature end-plate potentials and end-plate potentials were also blocked, but they recovered upon washing of the preparation with physiological solution.

摘要

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PLoS One. 2023 Jan 11;18(1):e0276557. doi: 10.1371/journal.pone.0276557. eCollection 2023.
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Neurotoxic acylpolyamines from spider venoms.来自蜘蛛毒液的神经毒性酰基多胺。
J Chem Ecol. 1993 Oct;19(10):2411-51. doi: 10.1007/BF00979674.