Wagner K
Acta Med Austriaca Suppl. 1979;6:277-81.
Secondary anemias due to infections, malignancies, endocrinopathies, hepatic and renal disorders, are discussed in terms of pathogenesis, diagnosis and treatment. Typical features for each type of secondary anemia are presented to enable a diagnosis by means of simple laboratory methods. Differential diagnosis is rather difficult due to complex mechanisms of pathogenesis. The differentiation of iron deficiency, lack of growth factors, and hemolysis is of utmost importance. Frequently too little diagnostic work up is contrasted by too much mostly unnecessary treatment. The significance of neuraminidases in infections needs further research.
本文从发病机制、诊断和治疗方面讨论了由感染、恶性肿瘤、内分泌疾病、肝脏和肾脏疾病引起的继发性贫血。介绍了每种类型继发性贫血的典型特征,以便通过简单的实验室方法进行诊断。由于发病机制复杂,鉴别诊断相当困难。缺铁、生长因子缺乏和溶血的鉴别至关重要。通常诊断检查做得太少,而大多是不必要的治疗却做得太多。神经氨酸酶在感染中的作用需要进一步研究。