Fereberger W
Acta Med Austriaca Suppl. 1979;6:281-6.
The leading symptom of dyserythropoiesis is an increased, ineffective erythropoiesis with characteristic morphological and functional features. The molecular background of the disturbances is unknown. There are similar structural and biochemical characteristics with different etiologic factors. In addition to rare, congenital forms acquired forms are observed frequently. A causal therapy is only known in deficiency and toxic states. There is an increased risk of transfusion hypersiderosis for the rest of patients with dyserythropoiesis. Among the acquired forms frequently premalignant diseases and tumours are found.
红细胞生成异常的主要症状是红细胞生成增加但无效，并伴有特征性的形态和功能特征。这种紊乱的分子背景尚不清楚。不同病因因素存在相似的结构和生化特征。除了罕见的先天性形式外，后天性形式也很常见。仅在缺乏和中毒状态下有已知的病因治疗方法。其余红细胞生成异常患者发生输血性铁过载的风险增加。在后天性形式中，常发现癌前疾病和肿瘤。
