Mu En, Liu Zhiyong, Ma Xiaochun
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2016 May;28(5):474-7.
Coagulopathy is very common in patients in intensive care unit (ICU) and often indicates organ dysfunction or underlying diseases.The application of traditional methods assessing the patients' coagulation status in ICU is limited because they can not reflect the whole process of coagulation.Thromboelastography (TEG),a point-of-care (POC) assay of coagulation,fibrinolysis and platelet function,developed in recent years has been widely used in organ transplant and cardiovascular surgery and so on.However,there is no standard for the use of TEG in ICU.The development and application of TEG in sepsis,multiple trauma,guiding blood transfusion,extracorporeal membrane oxygenation (ECMO),and anticoagulation monitoring were addressed in this review,and its value and application prospect in ICU were analyzed.
凝血功能障碍在重症监护病房(ICU)患者中非常常见,且常提示器官功能障碍或潜在疾病。传统方法用于评估ICU患者的凝血状态存在局限性,因为它们无法反映凝血的全过程。血栓弹力图(TEG)是近年来开发的一种用于检测凝血、纤溶和血小板功能的床旁检测(POC)方法,已广泛应用于器官移植和心血管手术等领域。然而,TEG在ICU中的使用尚无标准。本文综述了TEG在脓毒症、多发伤、指导输血、体外膜肺氧合(ECMO)及抗凝监测方面的发展与应用,并分析了其在ICU中的价值及应用前景。