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CT及68Ga-DOTA-NOC PET/CT表现为酷似淋巴瘤的小细胞肺癌:一例报告

Small cell lung cancer mimicking lymphoma in CT and 68Ga-DOTA-NOC PET/CT: A case report.

作者信息

Lu Liyan, Li Fengfang, Zhang Yamei, Wang Peng, Yin Xindao, Li Wenbin

机构信息

Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

出版信息

Medicine (Baltimore). 2018 Jun;97(25):e11159. doi: 10.1097/MD.0000000000011159.

DOI:10.1097/MD.0000000000011159
PMID:29924023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6024968/
Abstract

RATIONALE

Small cell lung cancer accounts for 15-20% of all lung cancers and is the most common pulmonary neuroendocrine neoplasm. Most small cell lung cancers arise from lobar or main bronchi, the most common manifestations of small cell lung cancer is a large mass centrally located within the lung parenchyma or a mediastinal mass involving the hilus. Small cell lung cancer is easily ignored by clinicians without lung parenchyma and hilus involvement. Here, we report a case of small cell lung cancer, which was misdiagnosed as the lymphoma in contrast enhanced CT and Ga-DOTA-NOC PET/CT imagings.

PATIENT CONCERNS

A 49-year-old male with chief complaint of discontinuous cough for 1 month.

DIAGNOSES

Small cell lung cancer.

INTERVENTIONS

Radiotherapy and chemotherapy were given thereafter.

OUTCOMES

The case had multiple enlarged lymph nodes due to tumor progression.

LESSONS

Small cell lung cancer is a malignant and progressive disease, and easy to be ignored in clinical. The case of small cell lung cancer without parenchyma and hilus involvement has never been reported before. Here, we report it and hope it provides a differential diagnosis for clinicians in the following similar cases.

摘要

理论依据

小细胞肺癌占所有肺癌的15%-20%,是最常见的肺神经内分泌肿瘤。大多数小细胞肺癌起源于叶支气管或主支气管,小细胞肺癌最常见的表现是肺实质中央的大肿块或累及肺门的纵隔肿块。无肺实质和肺门受累的小细胞肺癌很容易被临床医生忽视。在此,我们报告一例小细胞肺癌病例,在对比增强CT和Ga-DOTA-NOC PET/CT成像中被误诊为淋巴瘤。

患者情况

一名49岁男性,主诉间断咳嗽1个月。

诊断

小细胞肺癌。

干预措施

此后给予放疗和化疗。

结果

该病例因肿瘤进展出现多个肿大淋巴结。

经验教训

小细胞肺癌是一种恶性进展性疾病,在临床上容易被忽视。此前从未报道过无实质和肺门受累的小细胞肺癌病例。在此,我们报告该病例,希望能为临床医生在今后类似病例中提供鉴别诊断依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/6024968/329d25bba602/medi-97-e11159-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/6024968/627862e94d8b/medi-97-e11159-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/6024968/23bf298449de/medi-97-e11159-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/6024968/329d25bba602/medi-97-e11159-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/6024968/627862e94d8b/medi-97-e11159-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/6024968/23bf298449de/medi-97-e11159-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/6024968/329d25bba602/medi-97-e11159-g003.jpg

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