Han Jingzhe, Wang Tingting, Xie Yanan, Cao Duanhua, Kang Zhilei, Song Xueqin
Department of Neurology, Harrison International Peace Hospital, Hengshui Department of Angiocardiopathy, The Second Hospital of Hebei Medical University, Shijiazhuang Department of MRI, Harrison International Peace Hospital, Hengshui Department of Neurology, The Second Hospital of Hebei Medical University Institute of Cardiocerebrovascular Disease Neurological Laboratory of Hebei Province, Shijiazhuang, Hebei, China.
Medicine (Baltimore). 2018 Jun;97(25):e11192. doi: 10.1097/MD.0000000000011192.
Study reported an extremely rare case of trigeminal neuralgia, vestibular paroxysmia, and hemifacial spasm successively occurring in a patient with vertebrobasilar dolichoectasia (VBD).
A 66-year-old female patient presented with episodic vertigo for 20 days before she was admitted to our hospital. Vertigo suddenly occurred when the patient rotated her head 20 days ago, the symptoms of vertigo were improved after continuous 1 to 3 seconds, and similar symptoms were repeated in sleep and rest, with a frequency of 30 to 40 times per day. The patient had a history of hypertension with poor blood pressure control for more than 20 years.
The final diagnosis was vertebrobasilar dolichectasia, right trigeminal neuralgia, and vestibular paroxysmia.
Vitamin B1 (10 mg), methylcobalamin (0.5 mg), and carbamazepine (0.1 g) were given orally 3 times a day to relieve the symptoms.
On the seventh day of drug treatment, the symptoms of paroxysmal vertigo and trigeminal neuralgia were completely relieved, but occasional episodes occurred during the follow-up period. Five months after discharge, right hemifacial spasm appeared in the patient, which did not affect the quality of life of the patient, so the patient did not choose further treatment. Six months after discharge, the patient was lost to follow-up.
Comprehensive treatment to control VBD risk factors, delay the progression of VBD, and improve clinical symptoms may have a better effect on such patients. However, further research is needed.
研究报告了一例极为罕见的病例,一名患有椎基底动脉延长扩张症(VBD)的患者先后出现了三叉神经痛、前庭阵发性眩晕和半面痉挛。
一名66岁女性患者在入院前20天出现发作性眩晕。20天前患者转头时突然出现眩晕,持续1至3秒后眩晕症状有所改善,睡眠和休息时也反复出现类似症状,每天发作30至40次。患者有高血压病史20多年,血压控制不佳。
最终诊断为椎基底动脉延长扩张症、右侧三叉神经痛和前庭阵发性眩晕。
口服维生素B1(10毫克)、甲钴胺(0.5毫克)和卡马西平(0.1克),每日3次以缓解症状。
药物治疗第7天,阵发性眩晕和三叉神经痛症状完全缓解,但随访期间偶有发作。出院5个月后,患者出现右侧半面痉挛,未影响患者生活质量,因此患者未选择进一步治疗。出院6个月后,患者失访。
综合治疗以控制VBD危险因素、延缓VBD进展并改善临床症状,对此类患者可能有更好的效果。然而,仍需进一步研究。