Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Friendship Road, Yuanjiagang, Yuzhong District, Chongqing, 400016, China.
Department of Neurology, 363 Hospital, Chengdu, China.
J Neurol. 2018 Aug;265(8):1916-1921. doi: 10.1007/s00415-018-8929-1. Epub 2018 Jun 20.
To assess the value of triple stimulation technique (TST) for diagnose of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
Seven clinically suspected CIDP patients who did not fulfill EFNS/PNS electrodiagnostic criteria for demyelinating neuropathy were enrolled in our study. Routine nerve conduction studies, lumbar puncture, spinal cord magnetic resonance imaging and TST were detected. The patients were being treated with oral prednisone starting at 1 mg/kg daily. The overall disability sum score was performed to evaluate the effect of corticosteroids.
Twenty-eight motor nerves were tested with TST, two conduction blocks (CBs) were detected between the root emergence and the Erb point in six patients respectively and one CB was detected in one patient. Symptoms of all seven patients improved after treatment with oral prednisone.
TST can detect CBs located between the root emergence and the Erb point. TST is useful for early diagnosis of CIDP.
评估三刺激技术（TST）在诊断慢性炎症性脱髓鞘性多发性神经病（CIDP）中的价值。
本研究纳入了 7 例临床疑似 CIDP 但不符合 EFNS/PNS 脱髓鞘神经病电诊断标准的患者。对其进行常规神经传导研究、腰椎穿刺、脊髓磁共振成像和 TST 检测。患者开始口服泼尼松龙治疗，起始剂量为 1mg/kg/日。采用总体残疾评分来评估皮质类固醇的疗效。
对 28 条运动神经进行了 TST 检测，在 6 例患者中分别在神经根发出处和 Erb 点之间检测到 2 个传导阻滞（CB），在 1 例患者中检测到 1 个 CB。所有 7 例患者在接受泼尼松龙口服治疗后症状均改善。
TST 可检测到神经根发出处和 Erb 点之间的 CB。TST 对 CIDP 的早期诊断有用。
